DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6388 and AT3G02320

DIOPT Version :9

Sequence 1:	NP_609566.1	Gene:	CG6388 / 34656	FlyBaseID:	FBgn0032430	Length:	578	Species:	Drosophila melanogaster
Sequence 2:	NP_186881.2	Gene:	AT3G02320 / 820451	AraportID:	AT3G02320	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	618	Identity:	239/618 - (38%)
Similarity:	339/618 - (54%)	Gaps:	76/618 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEVDEEKPQIIAENPNENVIRERNAEIVSGGNVFYNPVQEFNRDLSIAALNVYRQRLTKERSEKA 65
            ||.|.....:|.|...|.::.::|       .||:|..|..|||:|||.|..:..:..:|...|:
plant     1 METDLNDYTVIKEGEAEILMHKKN-------QVFFNKAQVNNRDMSIAVLREFLSKRKQEHEAKS 58

  Fly    66 LKKQRKKVKEQEDEKTTPVPEDPPV--------YEAGTRYEDG---------------------- 100
            .|:.|...|..|.:.:....|:.|.        :|..:  |||
plant    59 SKRTRPASKVIEKDASEASKEETPSENGMNNGDHEVAS--EDGPSSVSKDPAKTTERFAPREPKP 121

  Fly   101 LRILEALAATGLRSIRYAQEIAGVRQIVANDLSRQAVASINTNIRHNKVEEL--IEPSHSDAMTL 163
            .::||||:|:|||::|||:||.|:.|:||.|....:|.:...||:.|....:  :|..|:||.
plant   122 PKVLEALSASGLRALRYAREIEGIGQVVALDNDLASVEACQRNIKFNGSVAISKVESHHTDAR-- 184

  Fly   164 MYLSTQPEKRFDAVDLDPYGCPNRFLDGAMQCLVDGGLLLVTATDMAVLAGNAPEACYVKYGSVP 228
            :::.|.| |.||.|||||||.|:.|||.|:|.:.|||||:.||||||||.|...|.||.||||.|
plant   185 VHMLTHP-KEFDVVDLDPYGSPSIFLDSAIQSVTDGGLLMCTATDMAVLCGGNGEVCYSKYGSYP 248

  Fly   229 LRMKCCHEMALRILLHCIESHANRYGKYIEPLLSISADFYIRIFVRVYVGQAQCKLSMSKQSWIY 293
            ||.|.||||||||||..||||||||.:||.|:||:..|||:|:|||||...:..|.:..|.|::|
plant   249 LRAKYCHEMALRILLASIESHANRYKRYIVPVLSVQMDFYVRVFVRVYTSASAMKNTPLKLSYVY 313

  Fly   294 QCTGCETFTLQPLGITKPNPTAGNPQQLKFGIPTGPAVNSQCEHCGHRHHLGGPIWSAPIHNPEF 358
            ||.||::|.|||:|.:.|...:     :::....||.|...|.|||.::::||||||||:|:||:
plant   314 QCIGCDSFHLQPVGRSLPKNNS-----VRYLPAIGPVVKQDCNHCGKKYNMGGPIWSAPMHDPEW 373

  Fly   359 VQDLLTAVQETTLQSLGTQRRIVGVLSMVQEELQDVPLYYTPDKLCCVLKLEIVPMLKFRSAILH 423
            |..:|.:| ::.........||..||:.|.|||.||||:.:...||..||........||||:::
plant   374 VTSILNSV-KSMKDRYPAYDRISAVLTTVSEELLDVPLFLSLHNLCATLKCISPSAAMFRSAVIN 437

  Fly   424 AGYRVSYSHASKNSLKTNAPPAVLWDILRSWSKRHPVNPERMIPGSPLAAILSKECTAVYEFDEL 488
            |.||:|.:|.:...:||:||..|:|||:|.|.|.||:..:.  |..|.:.|||||.:...:|..
plant   438 ANYRISGTHVNPLGMKTDAPMEVIWDIMRCWVKNHPIKAQS--PEQPGSVILSKEPSHEVDFSR- 499

  Fly   489 HPEANPKSRKSALSRFQENPTPHWGPGTRA--------TIMIGDNKLPKSYRNQNKKQRHKASEQ 545
            |..:..|::...::||..||..||||..||        ..:||...:     |.:..|.|   |:
plant   500 HIGSLSKAQAKKVARFLPNPEKHWGPKLRAGRQITSKHVSLIGHEAV-----NGHLSQHH---EE 556

  Fly   546 QAEDDQQDTPQAVDEYDGDVEHLPKQPKLEATA 578
            ..|:|::..|:  |.....|:     ||.:.||
plant   557 LKEEDEEAEPE--DNVQDKVD-----PKRQKTA 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6388	NP_609566.1	AdoMet_MTases	17..452	CDD:302624	194/466 (42%)
CG6388	NP_609566.1	DUF1764	<58..>103	CDD:285744	12/74 (16%)
AT3G02320	NP_186881.2	AdoMet_MTases	10..466	CDD:388410	196/473 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	341	1.000	Domainoid score	I241
eggNOG	1	0.900	-	-		E1_COG1867
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5632
Inparanoid	1	1.050	389	1.000	Inparanoid score	I503
OMA	1	1.010	-	-		QHG54291
OrthoDB	1	1.010	-	-		D1414511at2759
OrthoFinder	1	1.000	-	-		FOG0003425
OrthoInspector	1	1.000	-	-		otm3293
orthoMCL	1	0.900	-	-		OOG6_101071
Panther	1	1.100	-	-	LDO	PTHR10631
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2318
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840