Protein Alignment Trm1 and Trmt1l

DIOPT Version :10

• Sequence 1: NP_609566.1
• Gene: Trm1 / 34656
• FlyBaseID: FBgn0032430
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: XP_006250054.1
• Gene: Trmt1l / 304851
• RGDID: 1307890
• Length: 725
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 113/540 - (20%)
• Similarity: 204/540 - (37%)
• Gaps: 149/540 - (27%)

  Fly     5 EEKPQII----AENPNENVIRERNAEIVSGGNV--------FYNPVQEFNRDLSIAALNVYRQRL 57
            |.|.:.|    |::.|| |::|.:.:|....|.        ::||..:.||.:....|
  Rat   206 ETKSRYISASTAKSSNE-VLKETDTDIQVFPNYSIPQKTDSYFNPKMKLNRQIIFCTL------- 262

  Fly    58 TKERSEKALKKQRKKVKEQEDEKTTPVPEDPPVYEAGTRYEDGLRILEALAATGLRSIRYAQEIA 122
                  .||.::||.                            |..|:|..|||:..:::|:.:.
  Rat   263 ------AALAEERKP----------------------------LECLDAFGATGIMGLQWAKHLG 293

  Fly   123 GVRQIVANDLSRQAVASINTNIRHNKVEEL--------------------IEPSHSDAMTLMYLS 167
            ...::..|||:..:|..|..|...||::.:                    |:.:..||..||:|
  Rat   294 NAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDGLEDCSTAGDIQVTRMDANVLMHL- 357

  Fly   168 TQPEKRFDAVDLDPYGCPNRFLDGAMQCLVDGGLLLVTATDMAVLAGNAPEACYVKYGSVPLRMK 232
                :.||.:.|||:|....:||.|.:.:.:.|::.||:||::.|...|.......||...:|.:
  Rat   358 ----RSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTE 418

  Fly   233 CCHEMALRILLHCIESHANRYGKYIEPLLSISADFYIRIFVRVYVGQAQCKLSMSKQSWIYQCTG 297
            ...|:|.||::..:...|.|..|.:|.|.:::.:.::.:.|||..|......:..|..::..|..
  Rat   419 YYKELAARIVVAAVARAAARCNKGVEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQW 483

  Fly   298 CETFTLQPLG-ITKPNPTAGNPQQLKFGIPTGPAVNSQCEHCGHRHHLGGPIWSAPIHNPEFVQD 361
            ||....|..| :.:.||....|......:|...|:..            ||:||:.:.|..|::.
  Rat   484 CEERIFQKDGNMVEENPYKQLPCNCHGSMPGKTAIEL------------GPLWSSSLFNTGFLKR 536

  Fly   362 LL-------------------------------------TAVQE-----------TTL---QSLG 375
            :|                                     |..||           ||:   .:.|
  Rat   537 MLFESIHHGLDDIQPLIKTLIFESECTPQSQCSVHAPSNTNKQEENGVFVKTTDDTTIDIYSAQG 601

  Fly   376 TQRRIVGVLSMVQEELQDV-----PLYYTPDKLCCVLKLEIVPMLKFRSAILHAGYRVSYSHASK 435
            .::.....:::.:::..|.     |.||...: ..:..:.:..:.||...:..||:|||.:|...
  Rat   602 KRKSNEMAINVAKKQKTDASTAHPPFYYNIHR-HSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDP 665

  Fly   436 NSLKTNAPPAVLWDILRSWS 455
            ..::|:|.......||..:|
  Rat   666 MGIRTDASLTQFKSILLKYS 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trm1	NP_609566.1	AdoMet_MTases	17..452	CDD:473071	106/519 (20%)
Trmt1l	XP_006250054.1	TRM1	247..685	CDD:441472	102/496 (21%)