DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6405 and cibar1

DIOPT Version :9

Sequence 1:	NP_609564.1	Gene:	CG6405 / 34654	FlyBaseID:	FBgn0032428	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001003604.1	Gene:	cibar1 / 445210	ZFINID:	ZDB-GENE-040801-123	Length:	295	Species:	Danio rerio

Alignment Length:	308	Identity:	92/308 - (29%)
Similarity:	164/308 - (53%)	Gaps:	30/308 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KDDRVKIINERINITERHLMEMCSSFALVTRKMAKYRDSFDELAKSVKSYADDEEINESLCQGLK 77
            :|.:.|.|.|.|...|:|..::|..||...||.|:.||..|.|.|.:..|||.|..|  |..|||
Zfish    11 RDTQTKQIQENITSVEKHFGDLCQLFAAYVRKTARLRDKADLLVKEINVYADTETPN--LKCGLK 73

  Fly    78 SFTNAVTIMGDYMDINVHRLEHKIVNELAQFEQLCKSTRDNLRLAVIARDKEVLRQRQMLELKSK 142
            :|.:.:..:.||....|.|||.|::..|..:..:.|:.|::|:....||::|..:.:|:..::.:
Zfish    74 NFADQLAKVQDYRQAEVERLEVKVIEPLKAYGNIVKTKREDLKQTQSARNREAKQMQQLERMRQR 138

  Fly   143 FSANN---SAADSELFKAKMEVQRTNKEIDDIIGNFEQRKLRDLKQIISDFILIAMKQHTKALEI 204
            ..::.   |.|:|||.:|.|:..||.:::::.|.:||::|:||:|:::.:|:::.|..|.|||||
Zfish   139 NPSDRQIISQAESELQRATMDATRTTRQLEETIDDFEKQKIRDIKKVLGEFVMVEMAFHAKALEI 203

  Fly   205 LSASYYDIGTIDERDDFIEFQKLMKTKEELASRKTALKKGLRSQSMDSLEHEHLVSPLKRRPKLS 269
            .:.:|..|..:||..|...|:                      .|:...:::..:..::...|||
Zfish   204 YTTAYQHIQNVDEEGDLEVFR----------------------NSLHPPDYQSRLEIVRANSKLS 246

  Fly   270 --RSNRNLTGAG-INHGSKTEPEDETDEQDEEEDDEDEETEQSGEEDE 314
              |:..:::.:| :...:.:......||:|||||||||:..:...:||
Zfish   247 LNRTGTSMSKSGTMQSRTSSRQRKRDDEEDEEEDDEDEDDLEEVTDDE 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6405	NP_609564.1	FAM92	1..222	CDD:284207	72/211 (34%)
cibar1	NP_001003604.1	BAR_FAM92	10..220	CDD:153282	71/210 (34%)
		BAR-like. /evidence=ECO:0000250\|UniProtKB:A1XBS5	12..222		72/211 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..295		18/52 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595920
Domainoid	1	1.000	138	1.000	Domainoid score	I4819
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12234
Inparanoid	1	1.050	154	1.000	Inparanoid score	I4296
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005047
OrthoInspector	1	1.000	-	-		oto40620
orthoMCL	1	0.900	-	-		OOG6_107237
Panther	1	1.100	-	-	LDO	PTHR21223
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5493
SonicParanoid	1	1.000	-	-		X3571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.880