Protein Alignment CG6405 and CIBAR2

DIOPT Version :9

• Sequence 1: NP_609564.1
• Gene: CG6405 / 34654
• FlyBaseID: FBgn0032428
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_940893.1
• Gene: CIBAR2 / 339145
• HGNCID: 24781
• Length: 304
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 73/280 - (26%)
• Similarity: 143/280 - (51%)
• Gaps: 10/280 - (3%)

  Fly     7 LSFLNTKDDRVKIINERINITERHLMEMCSSFALVTRKMAKYRDSFDELAKSVKSYADDEEINES 71
            ::.:.::|.:|:::...:..||::..:.||..|..|||.|:.||..|:|.|.:..:|:.|  |..
Human     1 MNIVFSRDSQVRVMENTVANTEKYFGQFCSLLAAYTRKTARLRDKADQLVKQLIDFANSE--NPE 63

  Fly    72 LCQGLKSFTNAVTIMGDYMDINVHRLEHKIVNELAQFEQLCKSTRDNLRLAVIARDKEVLRQRQM 136
            |...::.|...:..:.||....|.|||.|:||.|..:....|.||..::.....::.|:.:..::
Human    64 LRATMRGFAEDLAKVQDYRQAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQLEKL 128

  Fly   137 LELKSKFSANN---SAADSELFKAKMEVQRTNKEIDDIIGNFEQRKLRDLKQIISDFILIAMKQH 198
            .:|:.|..::.   |.|::.:.:|.::..||..::::.:..|:::||:||::...||:.|.|..|
Human   129 EKLRQKSPSDQQMISQAETRVQRAAVDSSRTTLQLEETVDGFQRQKLKDLQKFFCDFVTIEMVFH 193

  Fly   199 TKALEILSASYYDIGTIDERDDFIEFQKLMKTKEELASRKTALKKGLRSQSMDSLEHEHLVSPLK 263
            .||:|:.|:::..:...|...|.::|:  .|.:.......|.|   |.:.|......:.|.|...
Human   194 AKAVEVYSSAFQTLEKYDLERDLLDFR--AKMQGVYGHYDTRL---LANTSPPPSVLQSLASQGT 253

  Fly   264 RRPKLSRSNRNLTGAGINHG 283
            .:.:|||:|.:......|||
Human   254 LQVQLSRANEDPEHPHANHG 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6405	NP_609564.1	FAM92	1..222	CDD:284207	58/217 (27%)
CIBAR2	NP_940893.1	BAR-like. /evidence=ECO:0000250|UniProtKB:A1XBS5	6..217		58/212 (27%)
		BAR_FAM92	6..216	CDD:153282	57/211 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159702
Domainoid	1	1.000	130	1.000	Domainoid score	I5207
eggNOG	1	0.900	-	-		E1_28HP5
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4562
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005047
OrthoInspector	1	1.000	-	-		otm40927
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21223
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3571
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.850