DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6405 and AgaP_AGAP009881

DIOPT Version :9

Sequence 1:	NP_609564.1	Gene:	CG6405 / 34654	FlyBaseID:	FBgn0032428	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_553768.3	Gene:	AgaP_AGAP009881 / 3292088	VectorBaseID:	AGAP009881	Length:	381	Species:	Anopheles gambiae

Alignment Length:	374	Identity:	125/374 - (33%)
Similarity:	202/374 - (54%)	Gaps:	57/374 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFRRGKLSFLNTKDDRVKIINERINITERHLMEMCSSFALVTRKMAKYRDSFDELAKSVKSYADD 65
            |.|.|..:.| ..|::.|.|.|||:..|:|..|:|.:||..|||:|:.||..||||.:.:.|.|.
Mosquito     1 MLRSGNTTTL-LCDEQTKFILERISTVEKHFGELCGAFAEYTRKVARMRDKTDELAHTTQDYCDT 64

  Fly    66 EEINESLCQGLKSFTNAVTIMGDYMDINVHRLEHKIVNELAQFEQLCKSTRDNLRLAVIARDKEV 130
            |::|.:|...|.|...|||::||:.|..|.|||.|||:||||:|.:||..:::::.|::.|||::
Mosquito    65 EKLNPTLTGALSSMAKAVTLLGDFHDARVKRLEAKIVSELAQYETVCKHCKEDVKEALLVRDKDL 129

  Fly   131 LRQRQMLELKSKFS-ANNSAADSELFKAKMEVQRTNKEIDDIIGNFEQRKLRDLKQIISDFILIA 194
            .:::|:.:.||:.. ...:..|:|:.|:.:||::..|||:..:..||::||.|||:::..|:||.
Mosquito   130 AKRKQLEQSKSRNGRLKRNTNDTEIIKSNLEVEKALKEIEHQVERFEKQKLHDLKELLLSFVLIE 194

  Fly   195 MKQHTKALEILSASYYDIGTIDERDDFIEFQKLMKTKEELASRKTALKKGLRSQSMDSLEHEHLV 259
            :|.||:|:|:|||:|.||..|||..|..:|:|::  :::....:..|:: ::||||.:|
Mosquito   195 LKMHTQAVEVLSATYQDISDIDESKDLQQFKKIL--QQDTVPDRYFLQR-IKSQSMGAL------ 250

  Fly   260 SPLKRRPKLSRSNRNLTGAGINHGSKTEPEDETDEQDEEEDDEDEETEQSGEEDEESGTATDDER 324
                          |.|.||.|.|.|.:..........:|.:|.|...:|.|:
Mosquito   251 --------------NATLAGFNTGRKNKSLSSNSLNSSQEQEEQEIATESSEQ------------ 289

  Fly   325 EPTQPGNQVPPRENVFGAKIRSASKDIATPSTSASATSAPSKPSRQTVK 373
            :.||                    |..||.|..::.||..|..|..|:|
Mosquito   290 QRTQ--------------------KKGATVSRRSNKTSIQSVESLDTLK 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6405	NP_609564.1	FAM92	1..222	CDD:284207	93/221 (42%)
AgaP_AGAP009881	XP_553768.3	BAR_FAM92	12..221	CDD:153282	88/208 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	185	1.000	Domainoid score	I7036
eggNOG	1	0.900	-	-		E1_28HP5
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12234
Inparanoid	1	1.050	201	1.000	Inparanoid score	I6179
OMA	1	1.010	-	-		QHG26087
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005047
OrthoInspector	1	1.000	-	-		oto107393
Panther	1	1.100	-	-	LDO	PTHR21223
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3571
TreeFam	1	0.960	-	-
	12	11.930