Protein Alignment Pkd2 and brv2

DIOPT Version :9

• Sequence 1: NP_609561.2
• Gene: Pkd2 / 34651
• FlyBaseID: FBgn0041195
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_648970.2
• Gene: brv2 / 39932
• FlyBaseID: FBgn0036712
• Length: 736
• Species: Drosophila melanogaster
• Alignment Length: 777
• Identity: 155/777 - (19%)
• Similarity: 284/777 - (36%)
• Gaps: 199/777 - (25%)

  Fly   192 KSVGSSTPPSPSRGHRA----PSI------------IAASALQNRAKTNRILYTTDEEVREALVE 240
            :|:..:|.|.....:||    |::            :.:..|.:...||.:|....:.:...|:.
  Fly    67 QSIDYATWPQEDPPYRAEEGGPTMDHIGYLKIRLRSLRSELLISEGHTNEMLNQKYKHIAGDLLL 131

  Fly   241 FSVFIIFLILTSLVVLSVRHTYMFYFNDTMKKLFTNREMVVAPSVTVGFEKLITVPDWWDYLKYN 305
            :..:.|.|:|  :|||...|| .:|..:.|::||.:.     .|||.|..::..:.....|:|
  Fly   132 YGSYFIALML--MVVLQEDHT-NYYNTNNMQRLFWDN-----TSVTFGLSQVYFIYQVHSYMK-- 186

  Fly   306 FLVTLHGDLTFMDDAQANLTSMPPEG---SEQGSEQGSEQGSEQSPEEV-VGEAPEE------AP 360
                    :|.::...|..|: ..||   .||..:.|..:..:..|.:. :|....|      ||
  Fly   187 --------ITLVEAFYAQKTN-GYEGWWAMEQWQKIGVVRLRQMRPVDCHIGLGKPEWDKKTYAP 242

  Fly   361 EMDRLQEDFKYNGNPYIDLRGHRRAKRQSGVDGNSEDGSEDVSGNYLKDDSDSIQANMSFHHLEG 425
            |. ||         ||     ||                                    .|:.|.
  Fly   243 EW-RL---------PY-----HR------------------------------------MHYTEK 256

  Fly   426 RVFLYENLLLGPPRLRQIRVRKESCYVNDAFIRYFNTCYAAYSSGAEDRKPMHKGSPFRTMHDLD 490
            ...:|:..         :....|..::|...:.|.:..|
  Fly   257 FWRIYDPF---------VPAEFEPSFLNGLLLNYDHYGY-------------------------- 286

  Fly   491 STPIWTVLAFYRTGGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIK 555
                  :|.:....||.|.:...|...:|.|..|:|..|||:.:....::..::|.:.::|..|.
  Fly   287 ------LLNYPEVAGYVVLMMSTKINCLKQIEYLRDYSWLDKNTSALFIDLTMYNADANLFTLIT 345

  Fly   556 LIAEIPPTGGVIPQAHLQTVKMYSFFTDRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFC 620
            |..|..|.|..:|:.|:.:|.|......||....:|...:.::||.:.....|:|.......:
  Fly   346 LRVENSPFGIQLPRVHVDSVSMLGNVETRSNSELLILFVYTVLVILFARGVFTKIWHHPAAAH-- 408

  Fly   621 SMLNILDCAILLGCYLALVYNIWHSFKVMSLTARAHSDVTYQSLDV------LCFWNIIYVDMMA 679
            ....::|.||    |:..|:     ..|:::.....:|...|.::.      |.|...:.:..|.
  Fly   409 EAWTMVDLAI----YILNVF-----LTVLAIMRDIETDALLQIIETATKGQYLDFQRPLRLHQML 464

  Fly   680 IL--AFLVWI---KIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLF---G 736
            .:  .|||.|   :::|.:.|......||.||....:.:|...::..:|.:|   :|:.|.   |
  Fly   465 FIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMA---IGITLAVPNG 526

  Fly   737 TKHPDFRNFITSILTMIRMILG--------DFQYNLIEQANRVLGPIYFLTYILLVFFILLNMFL 793
            .....|.:.:.|::|.:...:|        ||.:     ..|:||.:.:|..:.|:..||:|:|.
  Fly   527 NNAVVFSHMVQSVVTCMWYSMGFNGDIHPADFFH-----GGRILGILLYLALVFLLAIILMNVFA 586

  Fly   794 AIIMETYNTVKGEITQGRSHLGSYI--------YRKLSGMLYWITHCGRK---RRHHPQASETE- 846
            ::|.:.:|.. ..|.:..|:..|..        |..|.|..:   .|.||   .|.|..|...|
  Fly   587 SVIYDYFNET-SRILKEHSNRSSITFLEFLHVEYADLFGDAF---RCLRKTYESRGHTVAENVEL 647

  Fly   847 DKDAEHDVGAAHD---ETHEIRKNMTPAEQQYFKDIPQGENQDMVRLNNRVGLLEEILEKLI 905
            :.:....:....|   ...|:::.:...||:......:||.  :.:|...:.|..||||:::
  Fly   648 ELNRRELIKFKRDLIKSPQELKRALLTEEQRSADYRLRGEK--LFKLMAILNLQVEILERMV 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkd2	NP_609561.2	PKD_channel	402..803	CDD:285288	81/422 (19%)
brv2	NP_648970.2	PKD_channel	169..596	CDD:285288	105/548 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456385
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10877
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840