Protein Alignment Pkd2 and F27C1.11

DIOPT Version :9

• Sequence 1: NP_609561.2
• Gene: Pkd2 / 34651
• FlyBaseID: FBgn0041195
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001362170.1
• Gene: F27C1.11 / 3565116
• WormBaseID: WBGene00017858
• Length: 1271
• Species: Caenorhabditis elegans
• Alignment Length: 580
• Identity: 103/580 - (17%)
• Similarity: 188/580 - (32%)
• Gaps: 185/580 - (31%)

  Fly    28 GASPRGTPTADSTPGDVTPARGPPPPPATKRVS-------IGVGSTRSAP--------------P 71
            |:.|   .|:.::.|:....|.|.|....:.||       :...:|.::|              |
 Worm   136 GSDP---ATSGNSSGNSIEKRQPLPSINNRYVSRRPQENGVSNSTTTTSPYVPKSYASKLKQTVP 197

  Fly    72 PAT---DPTGPPPTAGKPVRDTGPSTSPRPSLRDPGQSTS---DKPSTSDKPSTSDKPS---TSA 127
            |.|   :.|.......||.:||..|::.....:|.|:.||   .:.|...:..|..|..   ...
 Worm   198 PTTKLNNKTTSKEVNKKPKKDTAMSSAESNKTKDSGKGTSLNNSQQSERHEKMTEKKAQMIREEL 262

  Fly   128 RTTVREPGPSSSPSRPVSTRESGRITFQEAAPSTSAKVVKLAASEPRPAKPPEKEGFSLFK-RKK 191
            ||.:::....:|.|...|  |...|...|:.....|..::...|:....:.......|..: .||
 Worm   263 RTNLKQQNHQNSSSDQYS--EEDLIREAESDFEHDATGIQSGTSDEEEEEAATSNATSAAESAKK 325

  Fly   192 KSVGSS--TP----PSPSRGHRAPSIIAASALQNRAKTNRILYTTDEEVREALVEFSVFIIFLIL 250
            :|..||  ||    ||.|...|.||:       :::|.|:      ::.|:.:..
 Worm   326 RSAHSSHRTPAQKTPSTSESDRLPSL-------SKSKMNQ------KQRRKTMSR---------- 367

  Fly   251 TSLVVLSVRHTYMFYFNDTMKKLFTNREMVVAPSVTVGFEKLITVPDWWDYLKYNFLVTLHGDLT 315
                            .||..:...:|:...|...:    :|.|                    :
 Worm   368 ----------------QDTPYQATPSRQTTAATEAS----RLST--------------------S 392

  Fly   316 FMDDAQANLTSMPPEGSEQGSEQGSEQGSEQSPEEVVGEAPEEAPEMDRLQEDFKYNGNPYIDLR 380
            ...:..:..:|.|...|....|...::..::..:.:.|...||
 Worm   393 GSSEPHSRYSSRPTTSSTAVREVSDDEDEDEKHDMMNGTIDEE---------------------- 435

  Fly   381 GHRRAKRQSGVDGNSEDGSEDVSGNYLKDDSDSIQANMSFHHLEGRVFLYENLLLGPPRLRQIRV 445
                           :.|:|:|.    .||.:|::...:.|..:             .||.....
 Worm   436 ---------------DSGNEEVD----DDDDESLRETPAIHTPD-------------TRLPTSTS 468

  Fly   446 RKESCYVNDAFIRYFNTCYAAYSSGAEDRKPM----HKGSPFRTMHDLDSTPI----WTVLAFYR 502
            ||.:.....:|....:..::.. ||..|::.:    .:..|:|.:...:...:    ..:.|.|:
 Worm   469 RKSTAGSARSFASESSRAWSRI-SGYSDKEQILPSDEEEDPYRDIGTAERERLGEAATKIQAAYK 532

  Fly   503 TGGYTVNLDY-----DKDRNVKIINDLKD--IHW---LDRGSRLCL-----VEFNLFNEN 547
              ||||...:     :|:|..:.|.|.:.  ||:   :..|:|..|     :.|.|..||
 Worm   533 --GYTVRKKHVQFLKEKERKEQEILDYEKQFIHYTFEVMLGNRFGLDFDTPLFFVLHGEN 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkd2	NP_609561.2	PKD_channel	402..803	CDD:285288	34/169 (20%)
F27C1.11	NP_001362170.1	DCX	26..94	CDD:340456
		DUF2967	<89..>407	CDD:371408	62/338 (18%)
		PLAT	564..684	CDD:381752	7/27 (26%)
		PLAT	713..823	CDD:238061

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900