| Sequence 1: | NP_609561.2 | Gene: | Pkd2 / 34651 | FlyBaseID: | FBgn0041195 | Length: | 924 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001244281.1 | Gene: | Pkd1 / 24650 | RGDID: | 3333 | Length: | 4292 | Species: | Rattus norvegicus |
| Alignment Length: | 1040 | Identity: | 198/1040 - (19%) |
|---|---|---|---|
| Similarity: | 348/1040 - (33%) | Gaps: | 269/1040 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 42 GDVTPARGPPP---PPATKRVSIGVGST--------------RSAPPPATDPTGPPPTAGKPVRD 89
Fly 90 TGPSTSPRPSLRD-------------PGQSTSDK-----------PS---TSDKPSTSDKPSTSA 127
Fly 128 RTTVREPGPSSSPSRP---VSTRESGRITFQEAAPSTSAKVVKLAASE--------PRPAKPPEK 181
Fly 182 EGFSLFKRKKKSVGSSTPPSPSRGHRAPSIIAASALQNRAKTNRILYTTD-----------EEVR 235
Fly 236 EALVEF------------------------------SVFIIFLILTSLVVLSVRHTYM------- 263
Fly 264 ----FYFNDTMKKLFTNRE--MVVAPSVTVGFEKLITV-PDWWDYLKYNFLVTLHGDLTFMDDAQ 321
Fly 322 ANLTSMPPEGSEQGSEQGSEQGSEQSPEEVVGEAPEEAPEMDRLQEDFK------------YNGN 374
Fly 375 PYIDLRGHRRAKR-QSGVDGNSEDGSEDVSGNYLKDDSDSIQANMSFHHLEGRVFLYENLLLGPP 438
Fly 439 RLRQIRVRKESCYVNDAFIRYFNTCYAAYSSGAED-----RKPMHKGSP--FRTMHDLDSTPIWT 496
Fly 497 VLAFYRTGGYTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIP 561
Fly 562 PTGGVIPQAHLQTVKMYSFFTDRSM-LMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFCS---- 621
Fly 622 -------MLNILDCA--ILLGCYLALVYNIWHSFKVMSLTARAHSDVTYQSLDVLCFWNIIYVDM 677
Fly 678 MAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDF 742
Fly 743 RNFITSILTMIRMIL----GDFQYNLIEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETYNTV 803
Fly 804 KGEITQGRSHLGSY--IYRKLSGMLYWITHCGRKRRHH----------PQASETEDKDAE--HDV 854
Fly 855 GAAHDETHEIRKNMTPAEQQYFKDIPQGENQDMVRLNNRVGLLEEILEKLINNMDDILKRVEKDY 919
Fly 920 919 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pkd2 | NP_609561.2 | PKD_channel | 402..803 | CDD:285288 | 86/425 (20%) |
| Pkd1 | NP_001244281.1 | LRRNT | 32..71 | CDD:214470 | |
| LRR_8 | 61..127 | CDD:290566 | |||
| leucine-rich repeat | 70..92 | CDD:275378 | |||
| LRR_4 | 72..108 | CDD:289563 | |||
| leucine-rich repeat | 93..116 | CDD:275378 | |||
| PCC | 97..2722 | CDD:188093 | |||
| leucine-rich repeat | 117..129 | CDD:275378 | |||
| LRRCT | 125..177 | CDD:214507 | |||
| WSC | 177..271 | CDD:214616 | |||
| PKD | 277..344 | CDD:279180 | |||
| CLECT | 406..530 | CDD:214480 | |||
| PKD | 927..1007 | CDD:214510 | |||
| PKD | 1017..1115 | CDD:214510 | |||
| PKD | 1124..1195 | CDD:279180 | |||
| PKD | 1214..1278 | CDD:279180 | |||
| PKD | 1289..1370 | CDD:214510 | |||
| PKD | 1378..1449 | CDD:279180 | |||
| PKD | 1471..1538 | CDD:214510 | |||
| PKD | 1546..1615 | CDD:279180 | |||
| PKD | 1635..1703 | CDD:279180 | |||
| PKD | 1718..1787 | CDD:279180 | |||
| PKD | 1807..1871 | CDD:279180 | |||
| PKD | 1886..1955 | CDD:279180 | |||
| PKD | 1974..2045 | CDD:279180 | |||
| PKD | 2062..2129 | CDD:279180 | |||
| GPS | 3002..3051 | CDD:197639 | |||
| PLAT_polycystin | 3109..3228 | CDD:238850 | |||
| PKD_channel | 3700..4102 | CDD:285288 | 87/428 (20%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166345338 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3599 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.740 | |||||