Protein Alignment bru1 and celf4

DIOPT Version :10

• Sequence 1: NP_723737.1
• Gene: bru1 / 34648
• FlyBaseID: FBgn0000114
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_031757481.1
• Gene: celf4 / 779831
• XenbaseID: XB-GENE-5873699
• Length: 488
• Species: Xenopus tropicalis
• Alignment Length: 580
• Identity: 232/580 - (40%)
• Similarity: 303/580 - (52%)
• Gaps: 140/580 - (24%)

  Fly   271 SNGTSSNNSLNVGNNNSNPSLGGSNSNALVSVGSNGIMSAAGLVNNNNNPCSANRNVVAMVDDDA 335
            :||...|:||     :|||:  |.         .||:..:.|           ....:.|.|.||
 Frog     9 ANGQPDNSSL-----SSNPT--GH---------MNGLTHSPG-----------GAATIPMKDHDA 46

  Fly   336 CFRLDTDATVTYGEKEPDPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGC 400
                                 ||:|:||:|:::||..|:.:|||:|.::.:.||:|:.||:.|||
 Frog    47 ---------------------IKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGC 90

  Fly   401 CFVTFYTRHAALKAQDALHNVKTLNGMYHPIQMKPADSENRNE-RKLFVGMLNKKLNENDVRKLF 464
            .|:|:..|.:|||||.|||..|||.||..|||:||||||:|.| ||||||||||:.:|:|||:||
 Frog    91 AFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLF 155

  Fly   465 EVHGAIEECTVLRDQNGQSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEK 529
            |..|.|||||:||..:|.|||||||.::: ||...|....|..::.|.|.:|.||||||||.||:
 Frog   156 EAFGNIEECTILRGPDGNSKGCAFVKYSS-HAEAQAAINALHGSQTMPGASSSLVVKFADTDKER 219

  Fly   530 EQKKIQQI--QANLWNLASNINIPLGQTATSVTTPILPNPPQQPSPVLGADAITPASIQLLQQLQ 592
            ..:::||:  |..::|                                      |.:||.
 Frog   220 TMRRMQQMAGQMGMFN--------------------------------------PMAIQF----- 241

  Fly   593 AVGLQHQLLQALTGLGAQQSSSATDTSAVAAAGLLTPMTVQNLAAIAAMTQPSLSNAAAAAAAAT 657
              |......|||      ....|...::||..|.|.||.....|.:..|...:::..|||....|
 Frog   242 --GAYGAYAQAL------MQQQAAIMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPT 298

  Fly   658 SPGSAQLTNTAALLWSDPNPM---------ASAYMSTAA------GLPQFGSASALSTSPL---- 703
            |.||.....||..:.|.|:|:         |.|....||      |:..:.:.|..:..||
 Frog   299 SGGSTPPGITAPAVPSIPSPIGVNGFTGIPAQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAY 363

  Fly   704 ASVALSAAAA--AAAG---------------KQIEGPEGCNLFIYHLPQEFTDTDLASTFLPFGN 751
            |.|...|..|  ||.|               :|.|||||||||||||||||.|.:|...||||||
 Frog   364 AGVQQYAGPAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFGN 428

  Fly   752 VISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVGTKRLKVQLKKPKD-SKPY 810
            |||:|||:|:.|:.||||||||||||.|||.||:||||||:|.||||||||:||| ::||
 Frog   429 VISSKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru1	NP_723737.1	RRM1_CELF1_2_Bruno	356..437	CDD:410040	42/80 (53%)
		SF-CC1	<435..789	CDD:273721	157/392 (40%)
		RRM_SF	443..524	CDD:473069	46/81 (57%)
		RRM3_Bruno_like	722..800	CDD:241084	60/77 (78%)
celf4	XP_031757481.1	RRM1_CELF3_4_5_6	42..128	CDD:410041	46/106 (43%)
		RRM2_CELF3_4_5_6	134..214	CDD:410043	45/80 (56%)
		RRM3_CELF3_4_5_6	399..477	CDD:241083	60/77 (78%)