Protein Alignment bru1 and celf1

DIOPT Version :9

• Sequence 1: NP_001260403.1
• Gene: bru1 / 34648
• FlyBaseID: FBgn0000114
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_012816629.1
• Gene: celf1 / 549906
• XenbaseID: XB-GENE-854036
• Length: 534
• Species: Xenopus tropicalis
• Alignment Length: 577
• Identity: 266/577 - (46%)
• Similarity: 327/577 - (56%)
• Gaps: 146/577 - (25%)

  Fly   321 CSANRNVVAMVDDDACFRLDTDATVTYGEKEPDPDNIKMFVGQVPKSMDESQLREMFEEYGAVHS 385
            ||.|.:.|:.         ..:.|:.:.: .||||:|||||||||:|..|.:|||:||:||||:.
 Frog    17 CSLNSSPVSK---------KMNGTMDHPD-HPDPDSIKMFVGQVPRSWSEKELRELFEQYGAVYE 71

  Fly   386 INVLRDKATG--ISKGCCFVTFYTRHAALKAQDALHNVKTLNGMYHPIQMKPADSENRN------ 442
            ||||||::..  .||||||:|||||.|||:||:||||:|.|.||:|||||||||||..|
 Frog    72 INVLRDRSQNPPQSKGCCFITFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNGGLNTV 136

  Fly   443 ----------ERKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQNGQSKGCAFVTFATKHAA 497
                      :|||||||::||.||||:|.:|...|.|||..:||..:|.|:|||||||.|:..|
 Frog   137 LYPEHPASVEDRKLFVGMVSKKCNENDIRAMFSQFGQIEESRILRGPDGMSRGCAFVTFTTRSMA 201

  Fly   498 ISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKI-QQIQ--------ANLW-NLASNINIPL 552
            ..||| .:.|.:.||||:||:|||||||||:||||:: ||:|        |::| |||
 Frog   202 QMAIK-AMHQAQTMEGCSSPIVVKFADTQKDKEQKRMTQQLQQQMQQLNAASMWGNLA------- 258

  Fly   553 GQTATSVTTPILPNPPQQPSPVLGADAITP----ASIQLLQQLQAVGLQHQLLQALTGLGAQQSS 613
                                   |..::.|    ..:|||||..:.|    .|.:|:||......
 Frog   259 -----------------------GLSSLAPQYLALYLQLLQQTASSG----NLNSLSGLHPMGGE 296

  Fly   614 SATD-TSAVAAAGLLTPMTVQNLAAIAAMTQPSLSNAAAAAAAATSPGSAQLTNTAAL-----LW 672
            .||. ||.      |..|.:|||||:||        ||:||....|.|||..|:::.|     ..
 Frog   297 YATGMTSG------LNAMQLQNLAALAA--------AASAAQNTPSAGSALTTSSSPLSILTSSG 347

  Fly   673 SDP--------NPMAS-AYMSTAAGLP---QFGSASAL----------------STSPLASVALS 709
            |.|        ||||| ..:.|.||..   ..||.:.:                ||....|.|.|
 Frog   348 SSPSSNNNSAVNPMASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSLSNGTGSTMEALSQAYS 412

  Fly   710 -----AAAA---------------AAAGKQIEGPEGCNLFIYHLPQEFTDTDLASTFLPFGNVIS 754
                 ||||               .|||.|.|||||.|||||||||||.|.||...|:|||||:|
 Frog   413 GIQQYAAAALPSLYNQSLLSQQGLGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVS 477

  Fly   755 AKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVGTKRLKVQLKKPK-DSKPY 810
            |||||||||:|||||||||:|||.|||.||::|||||:|.||||||||:.| |||||
 Frog   478 AKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru1	NP_001260403.1	RRM1_CELF1_2_Bruno	356..437	CDD:241075	57/82 (70%)
		ELAV_HUD_SF	359..808	CDD:273741	251/535 (47%)
		RRM2_Bruno_like	443..524	CDD:241080	46/80 (58%)
		RRM3_Bruno_like	722..800	CDD:241084	61/77 (79%)
celf1	XP_012816629.1	RRM1_CELF1_2_Bruno	42..125	CDD:241075	57/82 (70%)
		ELAV_HUD_SF	45..529	CDD:273741	249/532 (47%)
		RRM2_CELF1_2	147..227	CDD:241078	46/80 (58%)
		RRM3_CELF1_2	442..533	CDD:241082	70/90 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7190
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	405	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1209165at2759
OrthoFinder	1	1.000	-	-		FOG0000286
OrthoInspector	1	1.000	-	-		otm48626
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2990
SonicParanoid	1	1.000	-	-		X208
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100