DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bru1 and celf3

DIOPT Version :9

Sequence 1:	NP_001260403.1	Gene:	bru1 / 34648	FlyBaseID:	FBgn0000114	Length:	810	Species:	Drosophila melanogaster
Sequence 2:	XP_031746314.1	Gene:	celf3 / 549245	XenbaseID:	XB-GENE-5796618	Length:	462	Species:	Xenopus tropicalis

Alignment Length:	481	Identity:	216/481 - (44%)
Similarity:	300/481 - (62%)	Gaps:	44/481 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   353 DPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGCCFVTFYTRHAALKAQDA 417
            :||.||:|:||:|:::||..|:.:||::|.::.:.|::||.||:.|||.|:|:..|.:|||||.|
Frog     3 EPDAIKLFIGQIPRNLDEKDLKPIFEQFGKIYELTVIKDKFTGMHKGCAFLTYCARESALKAQSA 67

  Fly   418 LHNVKTLNGMYHPIQMKPADSENRNE-RKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQNG 481
            ||..|||.||..|||:||||||:|.| ||||||||.|:..:.|||::||..|.|:||||||..:|
Frog    68 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRRMFEPFGNIDECTVLRGPDG 132

  Fly   482 QSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQIQANLWNLAS 546
            .|||||||.|.|...|.:||. .|..::.:.|.:|.||||||||:||:..:::||: ||...:.|
Frog   133 TSKGCAFVKFQTHTEAQAAIN-ALHGSRTLPGASSSLVVKFADTEKERGLRRMQQV-ANQLGMFS 195

  Fly   547 NINIPLGQTATSVTTPILPNPPQQPSPVLGADA------ITPASIQLLQQLQAVGLQHQLLQALT 605
            .|.:..| ..::.|..:.....||.:.::.|.:      .|.|::| :||:..:.....:...:|
Frog   196 PIALQFG-AYSAYTQAVSDQLMQQQAALVAAHSAYLNPMATMAAVQ-MQQMATINPNGIIATPIT 258

  Fly   606 GLGAQQSSSATDTSAVAAAGLLTPMT-------VQNLAAIAAMT--QPSLSNAAAAAAAATSPGS 661
            .:....|||.|.|....||   ||::       |...:|:...:  |||   :.|.......|..
Frog   259 PINPITSSSGTSTPPTLAA---TPVSAIPATLGVNGYSAVPTQSTVQPS---SEAIYTNGLHPYP 317

  Fly   662 AQLTNTAALLWSDPNPMASAYMSTAAGLPQFGSASALSTSPLASVALSAAAA------AAAGKQI 720
            ||  :..|.|    :|:..||    ||:..: :|:..:...|.|.|.:.|.|      ....:|.
Frog   318 AQ--SPVAQL----DPLQQAY----AGMQHY-TAAYPAAYGLVSPAFTQAPAILPQQPPQQQQQR 371

  Fly   721 EGPEGCNLFIYHLPQEFTDTDLASTFLPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIK 785
            |||||||:|||||||||||:::...|||||||||||||:|:.|:.||||||||||||.|||.||:
Frog   372 EGPEGCNIFIYHLPQEFTDSEILQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPGSAQAAIQ 436

  Fly   786 AMNGFQVGTKRLKVQLKKPKD-SKPY 810
            ||||||:|.||||||||:||| ::||
Frog   437 AMNGFQIGMKRLKVQLKRPKDANRPY 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bru1	NP_001260403.1	RRM1_CELF1_2_Bruno	356..437	CDD:241075	41/80 (51%)
		ELAV_HUD_SF	359..808	CDD:273741	210/471 (45%)
		RRM2_Bruno_like	443..524	CDD:241080	44/81 (54%)
		RRM3_Bruno_like	722..800	CDD:241084	60/77 (78%)
celf3	XP_031746314.1	RRM1_CELF3_4_5_6	2..88	CDD:410041	44/84 (52%)
		half-pint	8..>375	CDD:130706	145/387 (37%)
		RRM2_CELF3_4_5_6	94..174	CDD:410043	43/80 (54%)
		RRM3_CELF3_4_5_6	373..451	CDD:241083	60/77 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1209165at2759
OrthoFinder	1	1.000	-	-		FOG0000286
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X208
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010