Protein Alignment bru1 and Celf3

DIOPT Version :10

• Sequence 1: NP_723737.1
• Gene: bru1 / 34648
• FlyBaseID: FBgn0000114
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_008759544.1
• Gene: Celf3 / 499669
• RGDID: 1563168
• Length: 501
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 221/520 - (42%)
• Similarity: 299/520 - (57%)
• Gaps: 83/520 - (15%)

  Fly   353 DPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGCCFVTFYTRHAALKAQDA 417
            :||.||:||||:|:.::|..|:.:||::|.:..:.|::||.||:.|||.|:|:..|.:|||||.|
  Rat     3 EPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSA 67

  Fly   418 LHNVKTLNGMYHPIQMKPADSENRNE-RKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQNG 481
            ||..|||.||..|||:||||||:|.| ||||||||.|:..:.||||:||..|.|:||||||..:|
  Rat    68 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDG 132

  Fly   482 QSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQIQANLWNLAS 546
            .|||||||.|.| ||...|...||..::.:.|.:|.||||||||:||:..:::||:...| .:.|
  Rat   133 TSKGCAFVKFQT-HAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQL-GMFS 195

  Fly   547 NINIPLGQTATSVTTPILPNPPQQPSPVLGADAITPASIQLLQQLQAVGLQHQLLQALTGLGAQ- 610
            .|.:..|  |.|..|..|   .||.:.::.|.:   |.:..:..:.||.:||.......||.|.
  Rat   196 PIALQFG--AYSAYTQAL---MQQQAALVAAHS---AYLSPMATMAAVQMQHMAAINANGLIATP 252

  Fly   611 -QSSSATDTSAVAAAGLLTPMTVQNLAAIAAM---------TQPSLSNAA-------------AA 652
             ..||.|.|....||   ||::    |..||:         |||:...|.             .|
  Rat   253 ITPSSGTSTPPAIAA---TPVS----AIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPDEA 310

  Fly   653 AAAATSPGSAQL---TNTAALLWS---DP----NPMASAYMSTAAGLPQFGSASALSTSPLASVA 707
            .:|..|.|.|.:   |::..::.|   .|    :|:..||    ||:..:.:|...:.|.:|...
  Rat   311 LSAERSAGEAPIMPQTHSWLVMLSAAQSPAAPVDPLQQAY----AGMQHYTAAYPAAYSLVAPAF 371

  Fly   708 LSAAAAAA--------------------------AGKQIEGPEGCNLFIYHLPQEFTDTDLASTF 746
            ....|..|                          ..:|.|||:|||:|||||||||||:::...|
  Rat   372 PQPPALVAQQPPPPPQQQQQQQQQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMF 436

  Fly   747 LPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVGTKRLKVQLKKPKD-SKPY 810
            :|||:|||||||:|:.|:.||||||||||||.|||.||:||||||:|.||||||||:||| ::||
  Rat   437 VPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY 501

  Fly   811  810
              Rat   502  501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru1	NP_723737.1	RRM1_CELF1_2_Bruno	356..437	CDD:410040	41/80 (51%)
		SF-CC1	<435..789	CDD:273721	161/414 (39%)
		RRM_SF	443..524	CDD:473069	46/81 (57%)
		RRM3_Bruno_like	722..800	CDD:241084	57/77 (74%)
Celf3	XP_008759544.1	RRM1_CELF3_4_5_6	2..88	CDD:410041	44/84 (52%)
		half-pint	8..491	CDD:130706	210/503 (42%)
		RRM2_CELF3_4_5_6	94..174	CDD:410043	45/80 (56%)
		RRM3_CELF3_4_5_6	412..490	CDD:241083	57/77 (74%)