Protein Alignment bru1 and celf4

DIOPT Version :10

• Sequence 1: NP_723737.1
• Gene: bru1 / 34648
• FlyBaseID: FBgn0000114
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_009293466.1
• Gene: celf4 / 436835
• ZFINID: ZDB-GENE-040718-300
• Length: 541
• Species: Danio rerio
• Alignment Length: 608
• Identity: 234/608 - (38%)
• Similarity: 313/608 - (51%)
• Gaps: 171/608 - (28%)

  Fly   292 GGSNSNALVSVGSNGIMSAAGLVNNNNNPCSANRNVVAMVDDDACFRLDTDATVTYGEKEPDPDN 356
            |.:::|.||    |||       ::.::|.|.  ..:.|.|.||
Zfish    16 GAASTNGLV----NGI-------SHTHSPASC--ATIPMKDHDA--------------------- 46

  Fly   357 IKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGCCFVTFYTRHAALKAQDALHNV 421
            ||:|:||:|:::||..||.:|||:|.::.:.||:|:.||:.|||.|:|:..|.:|||||.|||..
Zfish    47 IKLFIGQIPRNLDEKDLRPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCARESALKAQTALHEQ 111

  Fly   422 KTLNGMYHPIQMKPADSENRNE-RKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQNGQSKG 485
            |||.||..|||:||||||:|.| ||||||||||:..|:|||:|||..|:|||||:||..:|.|||
Zfish   112 KTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQCEDDVRRLFESFGSIEECTILRGPDGNSKG 176

  Fly   486 CAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQI--QANLWN----- 543
            ||||.::| ||...|....|..::.|.|.:|.||||||||.||:..:::||:  |..::|
Zfish   177 CAFVKYST-HAEAQAAISALHGSQTMPGASSSLVVKFADTDKERTIRRMQQMAGQMGIFNPMALQ 240

  Fly   544 ----------------LAS----------------------NIN--------------IPLGQTA 556
                            :||                      .||              .|.|.||
Zfish   241 FGAYGAYAQVQQQAALMASVGQGGYLSPMAAFAAAQMQHMATINGLPGAPMTPTSGGSTPPGITA 305

  Fly   557 ---TSVTTPILPN------PPQ---------------QPSPVLGADAITPASIQL----LQQLQA 593
               ||:.:||..|      |||               .|.||:...:.|..|.:|    :..||.
Zfish   306 PTVTSIPSPISVNGFTGLPPPQANGQAPAEAMFTNGIHPYPVVFMSSATEESKRLSPGCIPVLQE 370

  Fly   594 VGLQHQLLQALTGLGAQQSSSATDTSAVAAAGLLTPMTVQNLAAIAAMTQPSLSNAAAAAAAATS 658
            |..:....:.  |||..|.|.               ..||....::::::            |.|
Zfish   371 VVFREDSEKG--GLGVAQRSC---------------FGVQGSCFLSSLSE------------AQS 406

  Fly   659 PGSAQLTNTAALLWSDPNPMASAYMSTAAGLPQFGSASALSTSPLASVALSAAAAAAAGKQIEGP 723
            |       |||      :|:..||    ||:.|:.:|...:...: |.|..........:|.|||
Zfish   407 P-------TAA------DPLQQAY----AGVQQYAAAFPAAYGQI-SQAFPQPPPIIPQQQREGP 453

  Fly   724 EGCNLFIYHLPQEFTDTDLASTFLPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMN 788
            ||||||||||||||.|.:|...|||||||||:|||:|:.|:.||||||||||||.|||.||::||
Zfish   454 EGCNLFIYHLPQEFGDGELMQMFLPFGNVISSKVFVDRATNQSKCFGFVSFDNPGSAQAAIQSMN 518

  Fly   789 GFQVGTKRLKVQLKKPKD-SKPY 810
            |||:|.||||||||:||| ::||
Zfish   519 GFQIGMKRLKVQLKRPKDANRPY 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru1	NP_723737.1	RRM1_CELF1_2_Bruno	356..437	CDD:410040	43/80 (54%)
		SF-CC1	<435..789	CDD:273721	161/441 (37%)
		RRM_SF	443..524	CDD:473069	47/81 (58%)
		RRM3_Bruno_like	722..800	CDD:241084	59/77 (77%)
celf4	XP_009293466.1	RRM1_CELF3_4_5_6	42..128	CDD:410041	47/106 (44%)
		SF-CC1	<45..427	CDD:273721	150/449 (33%)
		RRM2_CELF3_4_5_6	134..214	CDD:410043	46/80 (58%)
		RRM3_CELF3_4_5_6	452..530	CDD:241083	59/77 (77%)