Protein Alignment bru1 and Celf5

DIOPT Version :10

• Sequence 1: NP_723737.1
• Gene: bru1 / 34648
• FlyBaseID: FBgn0000114
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: NP_001361632.1
• Gene: Celf5 / 319586
• MGIID: 2442333
• Length: 446
• Species: Mus musculus
• Alignment Length: 483
• Identity: 211/483 - (43%)
• Similarity: 276/483 - (57%)
• Gaps: 64/483 - (13%)

  Fly   353 DPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGCCFVTFYTRHAALKAQDA 417
            |.|.||:||||:|:.:.|..|:.:||::|.::.:.||:|..||:.|||.|:|:..|.:|:|||.|
Mouse     3 DLDAIKLFVGQIPRHLHEQDLKPLFEQFGRIYELTVLKDPHTGVHKGCAFLTYCARDSAIKAQTA 67

  Fly   418 LHNVKTLNGMYHPIQMKPADSENR--NERKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQN 480
            ||..|||.||..|||:||||||:|  .:||||||||||:.:|.||.:||:..|.|:||||||..:
Mouse    68 LHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPD 132

  Fly   481 GQSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQIQANLWNLA 545
            |.|||||||.|::...|.:||. .|..::.|.|.:|.||||||||.||:..:::||:...|..|.
Mouse   133 GSSKGCAFVKFSSHTEAQAAIH-ALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILT 196

  Fly   546 SNINIPL------GQTATSVTTPILPNPPQQPSPVLGADAITPASIQLLQQLQAVGLQHQLLQAL 604
            .::.:|.      .|......|.:|.......||.:   |..|..|   ||:.||        :|
Mouse   197 PSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGV---AFPPCHI---QQIGAV--------SL 247

  Fly   605 TGLGAQQSSSATDTSAVAAAGLLTPMTVQNLAAIAAMTQPSLSNAAAAAAAA----------TSP 659
            .||.|        |....|:||.:|              |.|..||.....|          ..|
Mouse   248 NGLPA--------TPIAPASGLHSP--------------PLLGTAAVPGLMAPIPNGFPGVLPFP 290

  Fly   660 GSAQLTNTAALLWSDPNPMASAYMSTA-----AGLPQFGSASALSTSPLASVALSAAAAA-AAGK 718
            ||.....|.......|.|..|..::..     :|:.|:  .:...|:.:|.||.|..... ...:
Mouse   291 GSHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQY--TAMYPTAAIAPVAHSVPQPPHLLQQ 353

  Fly   719 QIEGPEGCNLFIYHLPQEFTDTDLASTFLPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVA 783
            |.|||||||||||||||||.||:|...||||||:||:|||:|:.|:.||||||||||:|.|||.|
Mouse   354 QREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDHPASAQAA 418

  Fly   784 IKAMNGFQVGTKRLKVQLKKPKD-SKPY 810
            |:||||||:|.||||||||:||| ..||
Mouse   419 IQAMNGFQIGMKRLKVQLKRPKDPGHPY 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru1	NP_723737.1	RRM1_CELF1_2_Bruno	356..437	CDD:410040	40/80 (50%)
		SF-CC1	<435..789	CDD:273721	152/377 (40%)
		RRM_SF	443..524	CDD:473069	44/80 (55%)
		RRM3_Bruno_like	722..800	CDD:241084	59/77 (77%)
Celf5	NP_001361632.1	RRM1_CELF3_4_5_6	2..88	CDD:410041	43/84 (51%)
		PABP-1234	<9..358	CDD:130689	139/387 (36%)
		RRM2_CELF3_4_5_6	95..175	CDD:410043	44/80 (55%)
		RRM3_CELF3_4_5_6	357..435	CDD:241083	59/77 (77%)