Protein Alignment bru1 and Celf5

DIOPT Version :10

• Sequence 1: NP_723737.1
• Gene: bru1 / 34648
• FlyBaseID: FBgn0000114
• Length: 810
• Species: Drosophila melanogaster
• Sequence 2: XP_038934951.1
• Gene: Celf5 / 314647
• RGDID: 1565016
• Length: 446
• Species: Rattus norvegicus
• Alignment Length: 473
• Identity: 210/473 - (44%)
• Similarity: 276/473 - (58%)
• Gaps: 44/473 - (9%)

  Fly   353 DPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGCCFVTFYTRHAALKAQDA 417
            |.|.||:||||:|:.:.|..|:.:||::|.::.:.||:|..||:.|||.|:|:..|.:|:|||.|
  Rat     3 DLDAIKLFVGQIPRHLHEQDLKPLFEQFGRIYELTVLKDPHTGVHKGCAFLTYCARDSAIKAQTA 67

  Fly   418 LHNVKTLNGMYHPIQMKPADSENR--NERKLFVGMLNKKLNENDVRKLFEVHGAIEECTVLRDQN 480
            ||..|||.||..|||:||||||||  .:||||||||||:.:|.||.:||:..|.|:||||||..:
  Rat    68 LHEQKTLPGMARPIQVKPADSENRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPD 132

  Fly   481 GQSKGCAFVTFATKHAAISAIKVTLSQNKIMEGCTSPLVVKFADTQKEKEQKKIQQIQANLWNLA 545
            |.|||||||.|::...|.:||. .|..::.|.|.:|.||||||||.||:..:::||:...|..|.
  Rat   133 GSSKGCAFVKFSSHTEAQAAIH-ALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILT 196

  Fly   546 SNINIPL------GQTATSVTTPILPNPPQQPSPVLGADAITPASIQLLQQLQAVGLQHQLLQAL 604
            .::.:|.      .|......|.:|.......||.:   |..|..|   ||:..|        :|
  Rat   197 PSLTLPFSPYSAYAQALMQQQTTVLSTSGSYLSPGV---AFPPCHI---QQIGTV--------SL 247

  Fly   605 TGLGAQQSSSATDTSAVAAAGLLTPMTVQNLAAIAAMTQPSLSNAAAAAAAATSPGSAQLTNTAA 669
            .||.|        |....|:||.:|..:...|....||    |..:........|||.....|..
  Rat   248 NGLPA--------TPIAPASGLHSPPLLGTAAVPGLMT----SIPSGFPGVLPFPGSHPALETVY 300

  Fly   670 LLWSDPNPMASAYMSTA-----AGLPQFGSASALSTSPLASVALSAAAAA-AAGKQIEGPEGCNL 728
            .....|.|..|..::..     :|:.|:  .:...|:.:|.||.|..... ...:|.||||||||
  Rat   301 ANGLVPYPAQSPTVAETLHPAFSGVQQY--TAMYPTAAIAPVAHSVPQPPHLLQQQREGPEGCNL 363

  Fly   729 FIYHLPQEFTDTDLASTFLPFGNVISAKVFIDKQTSLSKCFGFVSFDNPDSAQVAIKAMNGFQVG 793
            |||||||||.||:|...||||||:||:|||:|:.|:.||||||||||:|.|||.||:||||||:|
  Rat   364 FIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFGFVSFDHPASAQAAIQAMNGFQIG 428

  Fly   794 TKRLKVQLKKPKD-SKPY 810
            .||||||||:||| ..||
  Rat   429 MKRLKVQLKRPKDPGHPY 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru1	NP_723737.1	RRM1_CELF1_2_Bruno	356..437	CDD:410040	40/80 (50%)
		SF-CC1	<435..789	CDD:273721	151/367 (41%)
		RRM_SF	443..524	CDD:473069	44/80 (55%)
		RRM3_Bruno_like	722..800	CDD:241084	59/77 (77%)
Celf5	XP_038934951.1	RRM1_CELF3_4_5_6	2..88	CDD:410041	43/84 (51%)
		PABP-1234	<9..358	CDD:130689	138/377 (37%)
		RRM2_CELF3_4_5_6	95..175	CDD:410043	44/80 (55%)
		RRM3_CELF3_4_5_6	357..435	CDD:241083	59/77 (77%)