Protein Alignment CG31760 and gpr158

DIOPT Version :10

• Sequence 1: NP_723730.2
• Gene: CG31760 / 34642
• FlyBaseID: FBgn0051760
• Length: 1093
• Species: Drosophila melanogaster
• Sequence 2: XP_002933190.2
• Gene: gpr158 / 779597
• XenbaseID: XB-GENE-950420
• Length: 1291
• Species: Xenopus tropicalis
• Alignment Length: 1095
• Identity: 251/1095 - (22%)
• Similarity: 413/1095 - (37%)
• Gaps: 322/1095 - (29%)

  Fly   173 STLYR----PLQVPINSERYESSRQKTDLAAS-----ILQEVGIIRHGG------LSD------- 215
            |.||:    .|:..:.|:.||.|...   .||     :|:.|.|:.||.      |..
 Frog    79 SFLYKGAAGELKAALCSQSYELSSLP---GASPGHPTLLRAVDILLHGTNFLNMMLQSNKSREHN 140

  Fly   216 ---------ALAKGLLTDDFITGARILALNLTNGAVQSYVWWVKGTAAEIQRYDEDGLQIGKKPA 271
                     ||.|.:|..:.......:|.|:...:....| :::.|..|.:.:.:| |.......
 Frog   141 WERDVEWYYALIKSILEGEPAIFRSAVAFNVEPSSHVPQV-FLRATREEGKIHLQD-LSASAHGP 203

  Fly   272 GSYPWFDD------ETSSPTLRSPKFAPSPPNNYYKGW--------------WTYPYFSCSQSR- 315
            |:..|..|      ..|.|.|.  |........:..||              |:.||..|...:
 Frog   204 GNATWEHDWLHTFKHRSRPHLH--KRLLHGAKTFDDGWKKGNSYVTDRSHVKWSSPYLECENGKY 266

  Fly   316 ---WLVSYSIAI----PPIGRHGLRGFISIDIDVSTLRVNQCEAEPYPFGSRRQKMQQLQTHNRL 373
               ||:|.|.|.    |.:.|. .||.:.:|:::..:.::||..|.:
 Frog   267 RPHWLLSLSAAFYGLKPNLVRE-FRGVLKVDVNLQNIDIDQCSNEGW------------------ 312

  Fly   374 GARRSLFLGSRMGAIDESTINDLQAFHSSHKCHRTSMVCDYRQPSAETPTVTGGKLLTTLTGSSS 438
                                     |..:|:|...|..|        .||...|.:|
 Frog   313 -------------------------FSGTHRCQHNSSKC--------IPTKGLGFVL-------- 336

  Fly   439 WTRGSYQCLCRGGFYSLRHPDGF---NGTIMEIAWQEQQDNISNYY------SEVFKCLPCAPGC 494
               |:|:|.|:.|||   :|.|.   ||.        |:.|:.|::      .|.:|||||..||
 Frog   337 ---GAYKCTCKAGFY---YPHGMFSENGF--------QRPNMVNHFPRGEISEEEYKCLPCREGC 387

  Fly   495 DTCTGPEPCLANYHWPFRISLLTISIGCACGTFVLAGYLFRHRRVKVFKVASPIFLMITLIGCAI 559
            ..||...||.|......||::::....|....|:....::..||.|..:.:..:.|.:.|.|..:
 Frog   388 SNCTDDAPCYAQEDKYLRIAIISFQAFCMLLDFISMLVVYSFRRAKSVRASGLVLLEVILFGSLL 452

  Fly   560 MYLEMVAIFPYLDTTWCIATKWTRHMGFCITYTSLLMKTWRVSLTYRVKSAHKIK-LNDQQLLQW 623
            :|..:|.::....|..||..:|.|.:|:...|.::.:|.:||...:..::|.:|. :...::::.
 Frog   453 LYFPVVILYFEPSTFRCILLRWVRLLGYATVYGTVTLKLYRVLKVFLSRTAQRIPYMTSGRVIRM 517

  Fly   624 MVPILLVMLIYLGTWTISATPTAE----VILD---QSQLKFKQCSYNWWDHSLAIGEVFFLAWGI 681
            :..|||::|.:|..||.:.....:    :|:.   ...|:||.|..:.||:.:|:.|..||.||:
 Frog   518 LSVILLLVLWFLVAWTSAVCQNMDRNIPLIVQGETSDNLQFKMCLIDRWDYMMAVAEFLFLLWGV 582

  Fly   682 RVCYNVRNAESLYNEARLISYAIYNIALVNIAMVVFHVMLFPNAG---PDYKYMLGFVRTQLSTT 743
            .:||.||...|.::|.|.:::|::|..:.:   .:||.:.|..|.   ||:..||.||.|.|:.|
 Frog   583 YLCYAVRTVPSAFHEPRYMAFAVHNELIFS---ALFHTIRFVLASKLQPDWMLMLFFVHTHLTVT 644

  Fly   744 TTIALVFGPKILRVFKGQGDKWDQKAKV---------------RSITASFSLNGVGLVPEESPDL 793
            .|:.|:..||..|......|  |..|:.               .|||:::|        |.|.|
 Frog   645 VTVGLLLIPKFSRSHNNPRD--DIAAEAYEDELDLGRSGSYLNSSITSAWS--------EHSLD- 698

  Fly   794 YQENEELKEQVQKLAHQIEFMKTVHMQMNNRHLKPKPGG----------YFTITSTSFQAPYSKN 848
               .|:::|:::||..|:|..|...|..||.||:.|...          ..|....|.....||.
 Frog   699 ---PEDIREELKKLYTQLEIYKRKKMIANNPHLQKKRCSKKGLGRSIMRRITEIPDSVSRQCSKE 760

  Fly   849 TVSTAQTQTGKDENSTPTKLKSPKGKVXRGQRSVKDCSIEIDGGQGRTTLVEDAIEFNFHL---A 910
            ...|  |..|..:|:..:..|.|:..| ...:|.::.|      :.:...::.:.....||   :
 Frog   761 EKDT--TDHGNPKNNVGSSKKHPQESVTHNAKSKEEPS------KHKLYSMKKSHSSYDHLRSES 817

  Fly   911 DTEKGLIVQE-------------DERP---GSDEE--------------EAALIAQFRRLFAPIL 945
            ||..|:..::             .::|   ||:.|              .|..::..::...|.|
 Frog   818 DTPNGISTEKVDVCKNSIYSPVNGKKPNKNGSELEAVSADNVPLVCKSASAHNLSVDKKPLHPSL 882

  Fly   946 --------------DDSLNLYYQLNDLDDTEHVRIHQTVAQMNDLTSSEEETMVTQVNSPSPPPV 996
                          |:||.|..:...::||:  :.|:|     |....|.:..|
 Frog   883 SVLQKSLSAVANSKDNSLGLRDKTQSVEDTD--KCHRT-----DSAYHEHQPSV----------- 929

  Fly   997 GVELLLPISSDSSTASSSLYAIHTPSP------AHPSGVLLMPQNLESPLLSGSDAITIT----- 1050
                        :|........||.||      .|.||:  |.|...||.|..|:.. ||
 Frog   930 ------------ATFDKEERQQHTSSPIEEIQKLHKSGI--MKQQAMSPHLPESEKF-ITAMGYK 979

  Fly  1051 -----EQV---ELHN-PP---------HHLQL--LEDE-NNTSCSLSSNLTDSKT 1084
                 |:|   |::: ||         .|:.:  ||.| |:||.|.|.:...||:
 Frog   980 DKFDIEEVCPWEMYDLPPSVPSENKVQKHVSIAPLESEKNHTSRSKSKSHNRSKS 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31760	NP_723730.2	FU	486..>508	CDD:214589	12/21 (57%)
		7tmC_GPR158-like	510..759	CDD:320420	71/259 (27%)
		TM helix 1	510..535	CDD:320420	4/24 (17%)
		TM helix 2	547..568	CDD:320420	5/20 (25%)
		TM helix 3	577..601	CDD:320420	6/23 (26%)
		TM helix 4	620..640	CDD:320420	6/19 (32%)
		TM helix 5	662..688	CDD:320420	10/25 (40%)
		TM helix 6	696..719	CDD:320420	5/22 (23%)
		TM helix 7	728..753	CDD:320420	10/24 (42%)
gpr158	XP_002933190.2	7tmC_GPR158-like	403..660	CDD:320420	71/259 (27%)
		TM helix 1	403..428	CDD:320420	4/24 (17%)
		TM helix 2	440..461	CDD:320420	5/20 (25%)
		TM helix 3	470..494	CDD:320420	6/23 (26%)
		TM helix 4	514..534	CDD:320420	6/19 (32%)
		TM helix 5	563..589	CDD:320420	10/25 (40%)
		TM helix 6	597..620	CDD:320420	6/25 (24%)
		TM helix 7	629..654	CDD:320420	10/24 (42%)