DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and rhbdl2

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_957498.1	Gene:	rhbdl2 / 792002	ZFINID:	ZDB-GENE-040426-732	Length:	294	Species:	Danio rerio

Alignment Length:	247	Identity:	70/247 - (28%)
Similarity:	120/247 - (48%)	Gaps:	43/247 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KDVRLLLLPENSTDSDGNPASVAFSAESHKKFIDDLTRTIDVGHVRRKRLWRVPWFILLMSFVQI 83
            |:|...:|||                |.|:.:::            |......|.||:|:|..::
Zfish    37 KNVSKWMLPE----------------ELHETYLE------------RANCCPPPIFIILISLAEL 73

  Fly    84 SL-----------HWI--ASECMQKVLIFKPEWNVEYWRLLTYMLLHSDYWHLSLNICFQCFIGI 135
            ::           .||  .:......|.::||...|.||.::||.:|:...|:..|:..|..:||
Zfish    74 AVFIYYAVWKPQKQWITLGTGIWDSPLTYRPEQRKEAWRFVSYMFVHAGVEHIMGNLLMQLLLGI 138

  Fly   136 CLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGASAGVYAMLGSHVPHLVLNFSQLSHRFA 200
            .||:....:.:.:|||.|.:|||||::...|...|:|||.||||::|.:..:.::||.::.....
Zfish   139 PLELVHKGFEVGMVYMCGVLAGSLASSIFDPFSALVGASGGVYALMGGYFMNAIVNFREMRVLLG 203

  Fly   201 --RIASLLILLLSDVGFTTYHFCHNHNRNPRTSLEAHIGGGVAGILCGFIVY 250
              ||..:::::.:||||..|.....|....:.|..||||||:||:..|::.:
Zfish   204 VFRILVIVLIVGTDVGFALYRRFIVHEAGLKVSFVAHIGGGIAGMTIGYVFF 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	52/147 (35%)
rhbdl2	NP_957498.1	Rhomboid	104..255	CDD:279958	54/150 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920