DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and rhbdf1b

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_021328201.1	Gene:	rhbdf1b / 563403	ZFINID:	ZDB-GENE-130531-6	Length:	894	Species:	Danio rerio

Alignment Length:	284	Identity:	65/284 - (22%)
Similarity:	112/284 - (39%)	Gaps:	44/284 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SAQVESNGASESNNNCVKDVRLLLLPENST------DSDGNPASVAFSAESHKKF--IDDLT--R 56
            ||.|..:...:..:.|.:|.|:.|.|.:.:      |....|....:|..:|...  ||.:.  |
Zfish   572 SAPVLGDKVRQYGSVCHQDPRICLEPASVSPHVWPDDISKWPICTRYSTGNHTNLPHIDCVITGR 636

  Fly    57 TIDVGHVRRKRLWRVPWFILLMSFVQISLHWIAS-----ECMQKVL----IFKPEWNVEYWRLLT 112
            ...:|...|..:....:    ..|::...|..|:     .||..|.    ...||...:::||..
Zfish   637 PCCIGTKGRCEITSREY----CDFMKGYFHEEATLCSQVHCMDDVCGLLPFLNPEIPDQFYRLWL 697

  Fly   113 YMLLHSDYWHLSLNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGASAGV 177
            .:.||:...|..:::|||..|...||...|..|::::|::.|:.|:||:|...|:...:|.:...
Zfish   698 SLFLHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLASAIFLPYRAEVGPAGSQ 762

  Fly   178 YAMLGSHVPHLVLNFSQLSHRFARIASLLILLLSDVGFTTYHFCHNHNRNPRTSLEAHIGGGVAG 242
            :.:|......|..::..|:..:.....|..::|....|....:..|.         |||.|.|:|
Zfish   763 FGILACLFVELFQSWQILARPWRAFTKLSCVVLFLFAFGLLPWIDNF---------AHICGFVSG 818

  Fly   243 ILCGFI-----------VYR-RLQ 254
            ....|.           :|| |||
Zfish   819 FFLSFAFLPYISFGRMDMYRKRLQ 842

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	35/155 (23%)
rhbdf1b	XP_021328201.1	Rhomboid_SP	130..348	CDD:315299
rhbdf1b	XP_021328201.1	Rhomboid	686..829	CDD:307698	37/151 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920