DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and rhbdl3

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_005166241.1	Gene:	rhbdl3 / 550128	ZFINID:	ZDB-GENE-050417-2	Length:	407	Species:	Danio rerio

Alignment Length:	241	Identity:	64/241 - (26%)
Similarity:	117/241 - (48%)	Gaps:	36/241 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 DDLTRTIDVGHVRRKRLWRV--------PWFILLMSFVQISL---------HWI----ASECMQK 95
            :.|.|.:|       |.|..        ||.:|.::..::.:         .|:    :...::.
Zfish   145 ETLPREVD-------RKWYFDSYTYCPPPWLMLAITITEVVVFMYYGLQLNRWVLQVSSPYFLKG 202

  Fly    96 VLIFKPEWNVEYWRLLTYMLLHSDYWHLSLNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLA 160
            .|.:.|:...:.||.|:|:.:|:...||.||:..|..:|:.||:..|..|:.:||:.|.:|||||
Zfish   203 PLPYHPQLRAQAWRFLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGALRIGLVYVCGALAGSLA 267

  Fly   161 NAWLQPHLHLMGASAGVYAMLGSHVPHLVLNFSQLSHRFA--RIASLLILLLSDVGFTTYHFCH- 222
            .:.......::|:|.||||::.:|:.::|:|:|.:..:|.  |:|..|:.:..:.|...:..|:
Zfish   268 VSVTDMTAPVVGSSGGVYALVSAHLANVVMNWSGMKCQFKLFRMAMALVCMSVEFGRAVWLRCYP 332

  Fly   223 -NHNRNPRTSLEAHIGGGVAGILCGFIVY----RRLQPANQKAIYF 263
             .....|..|..||:||...|:..|.:|.    :|||..:...|:|
Zfish   333 PAFPPCPNPSFVAHLGGVAVGLTLGVVVLQNYEQRLQEQSLFWIFF 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	48/152 (32%)
rhbdl3	XP_005166241.1	EFh	35..95	CDD:238008
		EF-hand_7	35..94	CDD:290234
		Rhomboid	208..362	CDD:279958	49/153 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577615
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950