DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and parla

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001014320.1	Gene:	parla / 541485	ZFINID:	ZDB-GENE-050327-8	Length:	383	Species:	Danio rerio

Alignment Length:	212	Identity:	43/212 - (20%)
Similarity:	81/212 - (38%)	Gaps:	60/212 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 WRVPWFILLMSFVQISLHWIAS------ECMQKVLIFKPEWNVEYWRLLTYMLLHSDYWHLSLNI 127
            ||||      :..:..:.:..|      .|:..||.....::|.:..:..|:|     |..|.:|
Zfish   184 WRVP------AMQRFLVKYFTSNPASKTRCLPMVLSSFSHYSVIHMVVNMYVL-----WTFSSSI 237

  Fly   128 CFQCFIGICLEVEQGHWRLAVVYMVGGVAGSL-------ANAWLQPHLHLMGASAGVYAMLGSHV 185
                   :.|   .|..:...:|:.|||..:.       |...|.|.|...|:...|.|.:.:.:
Zfish   238 -------VSL---LGREQFLALYLSGGVISTFVSYVFKTATGRLGPSLGASGSIMTVLAAVCTKI 292

  Fly   186 PHL--------VLNFSQLSHRFARIASLLILLLSDVGFTTYHFCHNHNRNPRTSLEAHIGGGVAG 242
            |..        |::||..:    .:.:|:.|.::.:......|.|          .||:||.:.|
Zfish   293 PEAKLGIVLLPVISFSAGN----ALKALVALDIAGLVLGWRFFDH----------AAHLGGALFG 343

  Fly   243 I-LCGF---IVYRRLQP 255
            : ..|:   :::|:.:|
Zfish   344 VWYIGYGHELIWRKREP 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	32/163 (20%)
parla	NP_001014320.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..75
parla	NP_001014320.1	Rhomboid	210..347	CDD:279958	34/165 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900