DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and stet

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	213	Identity:	62/213 - (29%)
Similarity:	105/213 - (49%)	Gaps:	33/213 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 PWFILLMSFVQISLHW--------------IASECMQKVLIFKPEWNVEYWRLLTYMLLHSDYWH 122
            |:||:|::.|::....              |.|:.|   .|::|:...|.||.|.||:||:.:.|
  Fly   222 PFFIILVTLVELGFFVYHSVVTGEAAPRGPIPSDSM---FIYRPDKRHEIWRFLFYMVLHAGWLH 283

  Fly   123 LSLNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGASAGVYAMLGSHVPH 187
            |..|:..|...|:.||:..|..|:|.:|..|.:||||..:...|.:.|:|||.||||:|.:|:.:
  Fly   284 LGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLAN 348

  Fly   188 LVLNFSQLSHRFARIASLLILLLSDVGFTTYHFCHNHNRNPRTSLE----------------AHI 236
            ::||:.|:.:...::..:|:.:..|.||..|...........:|.|                ||:
  Fly   349 VLLNYHQMRYGVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHL 413

  Fly   237 GGGVAGILCGFIVYRRLQ 254
            .|.:||:..|.:|.:..:
  Fly   414 AGAIAGLTIGLLVLKSFE 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	52/160 (33%)
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	53/165 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457251
Domainoid	1	1.000	84	1.000	Domainoid score	I2842
eggNOG	1	0.900	-	-		E1_COG0705
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D120647at6656
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	1	1.000	-	-		mtm1037
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.850