DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and rho-4

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_525084.1	Gene:	rho-4 / 32109	FlyBaseID:	FBgn0030318	Length:	417	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	71/266 - (26%)
Similarity:	128/266 - (48%)	Gaps:	38/266 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LLPENSTDSDGNPASVAFSAES--HKKFIDD-LTRTI---------------DVGHVRRKRLWRV 71
            :|..:..|:||:.....|.|.|  ||..:.: |||..               |..:.::..:...
  Fly   114 ILKRSDQDNDGHLDFEEFYAMSLRHKWMVRNMLTRYCRYVVPPPKPLEGDEPDGAYEKQMSICPP 178

  Fly    72 PWFILLMSFVQISLHWI------------------ASECMQKVLIFKPEWNVEYWRLLTYMLLHS 118
            |..::|.|.::|.:..:                  .|.....:.|:.|....|.||.::||.:|.
  Fly   179 PLTMVLFSIIEIIMFLVDVIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHV 243

  Fly   119 DYWHLSLNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGASAGVYAMLGS 183
            ...||.:|:..|.|:||.||:....||:.:||:.|.:|||:..:...|.:.|.|||.||||::.:
  Fly   244 GIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITA 308

  Fly   184 HVPHLVLNFSQLSHRFARIASLLILLLSDVGFTTYHFCHNHNRNPRTSLEAHIGGGVAGILCGFI 248
            |:..:::|:|::.:...::.:.|:...:|:|.:.|.  |..:::.:....||:.|.|||:|.|..
  Fly   309 HIATIIMNYSEMEYAIVQLLAFLVFCFTDLGTSVYR--HLTDQHDQIGYVAHLSGAVAGLLVGIG 371

  Fly   249 VYRRLQ 254
            |.|.|:
  Fly   372 VLRNLE 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	49/144 (34%)
rho-4	NP_525084.1	EFh_HEF	<57..197	CDD:355006	17/82 (21%)
		EFh	73..134	CDD:238008	5/19 (26%)
		Rhomboid	226..374	CDD:396315	50/149 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I2842
eggNOG	1	0.900	-	-		E1_COG0705
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D120647at6656
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	1	1.000	-	-		mtm1037
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.920