DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and Rhbdf2

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001100537.2	Gene:	Rhbdf2 / 303690	RGDID:	1309699	Length:	825	Species:	Rattus norvegicus

Alignment Length:	162	Identity:	37/162 - (22%)
Similarity:	72/162 - (44%)	Gaps:	17/162 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 CMQKVL----IFKPEWNVEYWRLLTYMLLHSDYWHLSLNICFQCFIGICLEVEQGHWRLAVVYMV 152
            |:.:|.    ...||...:::|:...:.||:...|..:::.||..|...||...|..|:::::::
  Rat   604 CLDEVCGLLPFLNPEIPDQFYRIWLSLFLHAGIVHCLVSVVFQMTILRDLEKLAGWHRISIIFIL 668

  Fly   153 GGVAGSLANAWLQPHLHLMGASAGVYAMLGSHVPHLVLNFSQLSHRFARIASL--LILLLSDVGF 215
            .|:.|:||:|...|:...:|.:...:.:|......|..::..|...:....:|  ::|.|...|.
  Rat   669 SGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWQLLERPWKAFFNLSAIVLFLFICGL 733

  Fly   216 TTYHFCHNHNRNPRTSLEAHIGGGVAGILCGF 247
            .           |.....|||.|.::|:|..|
  Rat   734 L-----------PWIDNIAHIFGFLSGMLLAF 754

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	33/144 (23%)
Rhbdf2	NP_001100537.2	Rhomboid_SP	98..302	CDD:403706
		Rhomboid	617..758	CDD:396315	35/149 (23%)
		MFS	718..>808	CDD:421695	12/48 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820