DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and Rhbdl2

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_898986.2	Gene:	Rhbdl2 / 230726	MGIID:	3608413	Length:	302	Species:	Mus musculus

Alignment Length:	209	Identity:	72/209 - (34%)
Similarity:	115/209 - (55%)	Gaps:	22/209 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 VRRKRLWRV-----PWFILLMSFVQISL-----------HWIASE--CMQKVLIFKPEWNVEYWR 109
            |||..|.|.     |.||:|:|..::::           .||..:  .::..|.:.||...|.||
Mouse    57 VRRTYLERANCLPPPLFIILISLAELAVFIYYAVWKPQKQWITLDTGILESPLTYCPEKREEAWR 121

  Fly   110 LLTYMLLHSDYWHLSLNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGAS 174
            .::|||:|:...|:..|:..|..:||.||:.....|:.:||:.|.:|||||::...|...|:|||
Mouse   122 FISYMLVHAGVQHIVGNLLMQIVLGIPLEMVHKGLRVGLVYLAGVLAGSLASSIFDPLKSLVGAS 186

  Fly   175 AGVYAMLGSHVPHLVLNFSQLSHRFARIASLLILLL--SDVGFTTY-HFCHNHNRNPRTSLEAHI 236
            .||||::|.:..::::||.::...|..:..|:|:|:  ||:||..| .|....|.:| .|..|||
Mouse   187 GGVYALMGGYFMNVIVNFREMIPAFGIVRLLVIILIVASDMGFALYRRFFVPANGSP-VSFAAHI 250

  Fly   237 GGGVAGILCGFIVY 250
            .||.||:..|:.|:
Mouse   251 AGGFAGMSIGYTVF 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	57/148 (39%)
Rhbdl2	NP_898986.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..38
Rhbdl2	NP_898986.2	Rhomboid	115..264	CDD:366759	56/149 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910