DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rho-6 and Rhbdl1

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_659065.1	Gene:	Rhbdl1 / 214951	MGIID:	2384891	Length:	373	Species:	Mus musculus

Alignment Length:	204	Identity:	57/204 - (27%)
Similarity:	97/204 - (47%)	Gaps:	17/204 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 RKRLWRVPWFILLMSFVQISL---------HWIAS----ECMQKVLIFKPEWNVEYWRLLTYMLL 116
            |.|....|.|:..::..||.:         .|:..    |.|:..|::.|......||.||||.:
Mouse   125 RHRTCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFM 189

  Fly   117 HSDYWHLSLNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGASAGVYAML 181
            |.....|..|...|..||:.||:..|..|::::|:.|.:||||..:.......::|.|.||||:.
Mouse   190 HVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALC 254

  Fly   182 GSHVPHLVLNFS--QLSHRFARIASLLILLLSDVGFTTY-HFCHN-HNRNPRTSLEAHIGGGVAG 242
            .:|:.::|:|::  :..::..|:...|:.:.|:||...: .|... ....|:.|..||:.|.|.|
Mouse   255 SAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVG 319

  Fly   243 ILCGFIVYR 251
            :..|..:.|
Mouse   320 VSMGLTILR 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	45/148 (30%)
Rhbdl1	NP_659065.1	Rhomboid	174..328	CDD:279958	46/153 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.880