DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-6 and rom-2

DIOPT Version :9

Sequence 1:	NP_788038.1	Gene:	rho-6 / 34640	FlyBaseID:	FBgn0032415	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001366679.1	Gene:	rom-2 / 183564	WormBaseID:	WBGene00004401	Length:	348	Species:	Caenorhabditis elegans

Alignment Length:	206	Identity:	57/206 - (27%)
Similarity:	105/206 - (50%)	Gaps:	18/206 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 PWFILLMSFVQISLH-----------WIASECMQKVLIFKPEWNV-EYWRLLTYMLLHSDYWHLS 124
            |.|::.:|.||::.:           |::........:...:::: |.|||.||.|::...:|:.
Worm   122 PIFLIFLSIVQLAFYLYYVVDSSEGVWLSGPIPTMSPLIVSQYHLPELWRLFTYCLINVGIFHII 186

  Fly   125 LNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGASAGVYAMLGSHVPHLV 189
            .||..|..||:.||:.. .||:.::|.:|.:.||:.:..|.|.:.|.|.:||.::::.||:..:.
Worm   187 FNILIQLAIGVPLELVH-RWRIYILYFMGVLFGSILSLALDPTVFLCGGAAGSFSLIASHITTIA 250

  Fly   190 LNFSQLSHRFARIASLLILLLSDVGFTTYH--FCHNHNRNPRTSLEAHIGGGVAGILCGFIVYRR 252
            .||.::.:...|:..|::....|.....|.  |.   .|..:.|:..|:||.|||||..||::|.
Worm   251 TNFKEMENATCRLPILIVFAALDYVLAVYQRFFA---PRIDKVSMYGHLGGLVAGILFTFILFRG 312

  Fly   253 LQPANQKAIYF 263
            .:|:....:.|
Worm   313 SKPSRFYTVSF 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-6	NP_788038.1	Rhomboid	106..251	CDD:279958	48/146 (33%)
rom-2	NP_001366679.1	EF-hand_7	21..82	CDD:404394
rom-2	NP_001366679.1	Rhomboid	165..311	CDD:396315	48/149 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162537
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.810