Protein Alignment Phae2 and KLK4

DIOPT Version :9

• Sequence 1: NP_001285871.1
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 64/263 - (24%)
• Similarity: 108/263 - (41%)
• Gaps: 44/263 - (16%)

  Fly    11 LLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLA 75
            |:|.|..|..||..     .:::.|:..:.:|.|:..::......:|:..:::..|:::||||..
Human    15 LILGVAGSLVSGSC-----SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ 74

  Fly    76 N------------RNQVLGSTLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTP 128
            |            .:|..||.:|..|::|.                :..|....:..|:.||...
Human    75 NSYTIGLGLHSLEADQEPGSQMVEASLSVR----------------HPEYNRPLLANDLMLIKLD 123

  Fly   129 TAFTWTAAVAPVKLPSSGVRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGS 193
            .:.:.:..:..:.:.|..........:.|||..:....|    |:.:..|:.::|.:.|     |
Human   124 ESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMP----TVLQCVNVSVVSEEVC-----S 179

  Fly   194 KGQD--VHTTNLCTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPSVYVQVSSFI 256
            |..|  .|.:..|.|........|..||||||:....|.|:||:||.||||...|.||..:..|.
Human   180 KLYDPLYHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFT 244

  Fly   257 TWI 259
            .||
Human   245 EWI 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	56/241 (23%)
		Tryp_SPc	32..262	CDD:238113	58/242 (24%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	58/242 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147447
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840