Protein Alignment Phae2 and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 95/278 - (34%)
• Similarity: 132/278 - (47%)
• Gaps: 36/278 - (12%)

  Fly     5 RHLATI---LLLAVCVSQG------SGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAAN 60
            |:.:||   |..:.|.||.      |...|....||:|||..|:.:..|:.||:.:|.||.|...
Human   290 RYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGT 354

  Fly    61 IINSNWLVTAAHC-LANRNQVLGSTLVAGSIAVAGTASTTQ---KRQITHYVINDLYTGGTVPYD 121
            :|::.|::||||| ...|.:||     .|....|||::..|   ...|...:||..||.....||
Human   355 LIDAQWVLTAAHCFFVTREKVL-----EGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYD 414

  Fly   122 IGLIYTPTAFTWTAAVAPVKLPSSG----VRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPII 182
            |.|:......|.:|.:.|..||..|    :..|  ..:.|:|.|.:|:..:.| .|:|.: :.:|
Human   415 IALMRLSKPLTLSAHIHPACLPMHGQTFSLNET--CWITGFGKTRETDDKTSP-FLREVQ-VNLI 475

  Fly   183 SLDSCAAALGSKGQDVHTT--NLCTGPLTGGTSFCTSDSGGPLV--QGN--VLIGIVSWGKLPCG 241
            ....|...|   ..|.:.|  .:|.|.|.||...|..|||||||  |.|  .|.|:.||| ..||
Human   476 DFKKCNDYL---VYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWG-TGCG 536

  Fly   242 QPNSPSVYVQVSSFITWI 259
            |.|.|.||.:|:..:.||
Human   537 QRNKPGVYTKVTEVLPWI 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	84/242 (35%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	9/30 (30%)
		Tryp_SPc	325..554	CDD:214473	83/241 (34%)