DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phae2 and TMPRSS5

DIOPT Version :9

Sequence 1:NP_001285871.1 Gene:Phae2 / 34638 FlyBaseID:FBgn0263235 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_110397.2 Gene:TMPRSS5 / 80975 HGNCID:14908 Length:457 Species:Homo sapiens


Alignment Length:236 Identity:75/236 - (31%)
Similarity:114/236 - (48%) Gaps:11/236 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 RVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLAN-RNQVLGSTLVAGSIAVAG 94
            |:|||::.|....|:..|:..|..|.|..:::...|:||||||:.: |...|.|..|...:....
Human   217 RIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHS 281

  Fly    95 TASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLPSSGVR-PTG-KADLFG 157
            .....|...:...:.:.||:.....||:.|:...||..::..|..|.||:.... |.| :..:.|
Human   282 AVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSG 346

  Fly   158 WGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGP 222
            ||.|..  |.:|...:.:...:|:.|...|.::....|. :....||.|.|.|....|..|||||
Human   347 WGHTHP--SHTYSSDMLQDTVVPLFSTQLCNSSCVYSGA-LTPRMLCAGYLDGRADACQGDSGGP 408

  Fly   223 LV--QGNV--LIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            ||  .|:.  |:|:||||: .|.:||.|.||.:|:.|:.||
Human   409 LVCPDGDTWRLVGVVSWGR-GCAEPNHPGVYAKVAEFLDWI 448

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Phae2NP_001285871.1 Tryp_SPc 31..259 CDD:214473 73/234 (31%)
Tryp_SPc 32..262 CDD:238113 74/235 (31%)
TMPRSS5NP_110397.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
SRCR_2 116..213 CDD:292133
Tryp_SPc 217..448 CDD:214473 73/234 (31%)
Tryp_SPc 218..451 CDD:238113 74/235 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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