DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae2 and Tmprss5

DIOPT Version :9

Sequence 1:	NP_001285871.1	Gene:	Phae2 / 34638	FlyBaseID:	FBgn0263235	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001346389.1	Gene:	Tmprss5 / 80893	MGIID:	1933407	Length:	455	Species:	Mus musculus

Alignment Length:	236	Identity:	80/236 - (33%)
Similarity:	121/236 - (51%)	Gaps:	11/236 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLAN-RNQVLGSTLVAGSIAVAG 94
            |:|||:|.|:...|:..|:..|..|.|.|:::..:|:||||||:.: |...|.|..|...:...|
Mouse   217 RIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPHWVVTAAHCMYSFRLSRLSSWRVHAGLVSHG 281

  Fly    95 TASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLPSSGVR-PTG-KADLFG 157
            .....|...:...:.:.||:.....||:.|:...|...::..|..|.||:.... |.| :..:.|
Mouse   282 AVRQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVGAVCLPAKEQHFPWGSQCWVSG 346

  Fly   158 WGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGP 222
            ||.|..:::.| ..|||:.. :|::|...|.::....|...|.. ||.|.|.|....|..|||||
Mouse   347 WGHTDPSHTHS-SDTLQDTM-VPLLSTYLCNSSCMYSGALTHRM-LCAGYLDGRADACQGDSGGP 408

  Fly   223 LV--QGNV--LIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            ||  .|:.  |:|:||||: .|.:||.|.||.:|:.|:.||
Mouse   409 LVCPSGDTWHLVGVVSWGR-GCAEPNRPGVYAKVAEFLDWI 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	78/234 (33%)
Phae2	NP_001285871.1	Tryp_SPc	32..262	CDD:238113	79/235 (34%)
Tmprss5	NP_001346389.1	SRCR_2	116..213	CDD:317845
Tmprss5	NP_001346389.1	Tryp_SPc	217..448	CDD:214473	78/234 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920