DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae2 and st14b

DIOPT Version :9

Sequence 1:	NP_001285871.1	Gene:	Phae2 / 34638	FlyBaseID:	FBgn0263235	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	242	Identity:	80/242 - (33%)
Similarity:	125/242 - (51%)	Gaps:	20/242 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RVVGGKAAAANSAPYIVS--MQYGGTHYCAANIINSNWLVTAAHCLANRNQVLGSTLVAGSIAVA 93
            |:||||.:.....|:.||  |:..| |.|.|::|:::||||||||:.:.:|...|......:.:.
Zfish   624 RIVGGKDSDEGEWPWQVSLHMKTQG-HVCGASVISNSWLVTAAHCVQDNDQFRYSQADQWEVYLG 687

  Fly    94 ----GTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLPS-SGVRPTGKA 153
                |..|.:.:|.:...:.:..|...:...||.|:...:..|....:.|:.||. :...|.||:
Zfish   688 LHNQGETSKSTQRSVLRIIPHPQYDHSSYDNDIALMELDSPVTLNQNIWPICLPDPTHYFPAGKS 752

  Fly   154 D-LFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTS 217
            . :.|||.. :..|.:.|..||:|: :.||:...| :.|...|...|.  :|.|.|:||...|..
Zfish   753 VWITGWGKL-REGSDAVPSVLQKAE-VRIINSTVC-SKLMDDGITPHM--ICAGVLSGGVDACQG 812

  Fly   218 DSGGPL--VQGN---VLIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            |||||:  ::||   .|.|:||||. .||:.|.|.||.:|:.:.:||
Zfish   813 DSGGPMSSIEGNGRMFLAGVVSWGD-GCGRRNRPGVYTRVTDYRSWI 858

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	78/240 (33%)
Phae2	NP_001285871.1	Tryp_SPc	32..262	CDD:238113	79/241 (33%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060
		Tryp_SPc	624..858	CDD:214473	78/240 (33%)
		Tryp_SPc	625..861	CDD:238113	79/241 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920