Protein Alignment Phae2 and PRSS56

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 84/276 - (30%)
• Similarity: 128/276 - (46%)
• Gaps: 46/276 - (16%)

  Fly    19 QGSG------LALDQPE------------------GRVVGGKAAAANSAPYIVSMQYGGTHYCAA 59
            :|||      |..|.||                  ||:|||.||...:.|::|.:|.||...|..
Human    68 RGSGRPRPQALLQDPPEPGPCGERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQPLCGG 132

  Fly    60 NIINSNWLVTAAHCLANR-NQVLGS-TLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDI 122
            .::.::|::|||||.... |::|.: ||..||     .....::..:...:.:..:...|...|:
Human   133 VLVAASWVLTAAHCFVGAPNELLWTVTLAEGS-----RGEQAEEVPVNRILPHPKFDPRTFHNDL 192

  Fly   123 GLIYTPTAFTWTAAVAPVKLPSSGVR-PTGKA-DLFGWGSTSKTNSPSYPKTLQEAKNIPIISLD 185
            .|:...|..:...:..||.||..... |.|.| .:.|||:..:....:  :.::||: :|::|.|
Human   193 ALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEA--EAVREAR-VPLLSTD 254

  Fly   186 SCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGPLV-------QGNVLIGIVSWGKLPCGQP 243
            :|..|||...:.  :|.||.|.|.||...|..||||||.       ...||.|:.|||. .||:|
Human   255 TCRRALGPGLRP--STMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGD-GCGEP 316

  Fly   244 NSPSVYVQVSSFITWI 259
            ..|.||.:|:.|..|:
Human   317 GKPGVYTRVAVFKDWL 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	75/239 (31%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	75/239 (31%)
		PksD	<178..600	CDD:442550	52/161 (32%)