Protein Alignment Phae2 and TPSB2

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_077078.5
• Gene: TPSB2 / 64499
• HGNCID: 14120
• Length: 275
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 80/285 - (28%)
• Similarity: 125/285 - (43%)
• Gaps: 50/285 - (17%)

  Fly     7 LATILLLAVCVSQGSGLALDQPEGR------VVGGKAAAANSAPYIVSMQYGG---THYCAANII 62
            :..:||||:.|......|...| |:      :|||:.|..:..|:.||::...   .|:|..::|
Human     1 MLNLLLLALPVLASRAYAAPAP-GQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLI 64

  Fly    63 NSNWLVTAAHCLANRNQVLGSTLVAGSIAVAGTASTTQKRQ-----------ITHYVINDLYTGG 116
            :..|::|||||:....:.|.:..|             |.|:           ::..:::..:...
Human    65 HPQWVLTAAHCVGPDVKDLAALRV-------------QLREQHLYYQDQLLPVSRIIVHPQFYTA 116

  Fly   117 TVPYDIGLIYTPTAFTWTAAVAPVKL-PSSGVRPTG-KADLFGWGSTSKTNSPSYPKTLQEAKNI 179
            .:..||.|:........::.|..|.| |:|...|.| ...:.|||..........|..|::.| :
Human   117 QIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVK-V 180

  Fly   180 PIISLDSCAAA--LGS-KGQDVHTTN---LCTGPLTGGTSFCTSDSGGPL---VQGNVL-IGIVS 234
            ||:....|.|.  ||: .|.||....   ||.|.....:  |..||||||   |.|..| .|:||
Human   181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDS--CQGDSGGPLVCKVNGTWLQAGVVS 243

  Fly   235 WGKLPCGQPNSPSVYVQVSSFITWI 259
            ||: .|.|||.|.:|.:|:.::.||
Human   244 WGE-GCAQPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	72/254 (28%)
TPSB2	NP_077078.5	Tryp_SPc	31..268	CDD:238113	72/254 (28%)