Protein Alignment Phae2 and PRSS22

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 87/275 - (31%)
• Similarity: 137/275 - (49%)
• Gaps: 25/275 - (9%)

  Fly     2 WRHRHLA-TILLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSN 65
            ||.|..: ..:|.|..:.........|...|||||:.:..:..|:|||:|..|||:||.:::.|.
Human   127 WRARGSSPPAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSR 191

  Fly    66 WLVTAAHCLA-NRNQVLGSTLVAGSIAVAGTASTTQKRQITHYVINDLYT---GGTVPYDIGLIY 126
            |::|||||.. |.|:....:::.|:..:....|.:||..:.....:.:|:   |...  ||.|:.
Human   192 WVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACA--DIALVR 254

  Fly   127 TPTAFTWTAAVAPVKLPSSGVR--PTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCA- 188
            ...:..::..|.|:.||.:.:.  |.....:.||||........:|:|||:.| :|||..:.|:
Human   255 LERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLK-VPIIDSEVCSH 318

  Fly   189 -----AALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGPL---VQGN-VLIGIVSWGKLPCGQPN 244
                 |..|...:|:    ||.|.|.|....|..||||||   |.|. :|.||:|||: .|.:.|
Human   319 LYWRGAGQGPITEDM----LCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGE-GCAERN 378

  Fly   245 SPSVYVQVSSFITWI 259
            .|.||:.:|:..:|:
Human   379 RPGVYISLSAHRSWV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	80/244 (33%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	80/244 (33%)