DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phae2 and KLK6

DIOPT Version :9

Sequence 1:NP_001285871.1 Gene:Phae2 / 34638 FlyBaseID:FBgn0263235 Length:265 Species:Drosophila melanogaster
Sequence 2:NP_001012982.1 Gene:KLK6 / 5653 HGNCID:6367 Length:244 Species:Homo sapiens


Alignment Length:233 Identity:70/233 - (30%)
Similarity:102/233 - (43%) Gaps:12/233 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 QPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLANRNQVLGSTLVAGSIA 91
            :.:.::|.|......|.||..::...|...|...:|:..|::|||||.....||.     .|...
Human    17 EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVF-----LGKHN 76

  Fly    92 VAGTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLPSSGVRPTGKADLF 156
            :....|:.::..:...||:..|...:...||.|:........:..:.|:.|.......|....:.
Human    77 LRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHIL 141

  Fly   157 GWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGG 221
            |||   ||....:|.|:|.| .|.::|.:.|..|.  .|| :....||.|....|...|..||||
Human   142 GWG---KTADGDFPDTIQCA-YIHLVSREECEHAY--PGQ-ITQNMLCAGDEKYGKDSCQGDSGG 199

  Fly   222 PLVQGNVLIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            |||.|:.|.|:||||.:|||....|.||..|..:..||
Human   200 PLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Phae2NP_001285871.1 Tryp_SPc 31..259 CDD:214473 68/227 (30%)
Tryp_SPc 32..262 CDD:238113 70/228 (31%)
KLK6NP_001012982.1 Tryp_SPc 23..237 CDD:214473 68/225 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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