Protein Alignment Phae2 and KLK6

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 70/233 - (30%)
• Similarity: 102/233 - (43%)
• Gaps: 12/233 - (5%)

  Fly    27 QPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLANRNQVLGSTLVAGSIA 91
            :.:.::|.|......|.||..::...|...|...:|:..|::|||||.....||.     .|...
Human    17 EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVF-----LGKHN 76

  Fly    92 VAGTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLPSSGVRPTGKADLF 156
            :....|:.::..:...||:..|...:...||.|:........:..:.|:.|.......|....:.
Human    77 LRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHIL 141

  Fly   157 GWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGG 221
            |||   ||....:|.|:|.| .|.::|.:.|..|.  .|| :....||.|....|...|..||||
Human   142 GWG---KTADGDFPDTIQCA-YIHLVSREECEHAY--PGQ-ITQNMLCAGDEKYGKDSCQGDSGG 199

  Fly   222 PLVQGNVLIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            |||.|:.|.|:||||.:|||....|.||..|..:..||
Human   200 PLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	70/228 (31%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	68/225 (30%)