Protein Alignment Phae2 and KLK7

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 87/269 - (32%)
• Similarity: 125/269 - (46%)
• Gaps: 41/269 - (15%)

  Fly    10 ILLLAVCVSQGSGLALDQPEG-RVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHC 73
            ||||::.:.    .|.::.:| :::.|...|..|.|:.|::..|...:|...::|..|::|||||
Human    11 ILLLSLALE----TAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC 71

  Fly    74 LANRNQV-LGSTLVAGSIAVAGTAS--------TTQKRQITHYVINDLYTGGTVPYDIGLIYTPT 129
            ..|...| |||..:....|....||        :||    ||  :|||.          |:...:
Human    72 KMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQ----TH--VNDLM----------LVKLNS 120

  Fly   130 AFTWTAAVAPVKLPSSGVRPTGKADLFGWGSTSKTNSP--SYPKTLQEAKNIPIISLDSCAAALG 192
            ....::.|..|:|||....|.....:.|||:|:   ||  ::|..|. ..::.:||...|....
Human   121 QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTT---SPDVTFPSDLM-CVDVKLISPQDCTKVY- 180

  Fly   193 SKGQD-VHTTNLCTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPSVYVQVSSFI 256
               :| :..:.||.|......:.|..|||||||....|.|:||||..||||||.|.||.||..|.
Human   181 ---KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242

  Fly   257 TWIAANQKK 265
            .||....||
Human   243 KWINDTMKK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	79/241 (33%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	77/239 (32%)