Protein Alignment Phae2 and PRSS2

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 84/273 - (30%)
• Similarity: 126/273 - (46%)
• Gaps: 35/273 - (12%)

  Fly    10 ILLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCL 74
            :||:...|:.......|. :.::|||.....||.||.||:. .|.|:|..::|:..|:|:|.||.
Human     3 LLLILTFVAAAVAAPFDD-DDKIVGGYICEENSVPYQVSLN-SGYHFCGGSLISEQWVVSAGHCY 65

  Fly    75 A--------------NRNQV-LGSTLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDIGL 124
            .              :|.|| ||...:.   .:.|........:|   :.:..|...|:..||.|
Human    66 KSAINSKLSGRGCEYHRIQVRLGEHNIE---VLEGNEQFINAAKI---IRHPKYNSRTLDNDILL 124

  Fly   125 IYTPTAFTWTAAVAPVKLPSSGVRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAA 189
            |...:.....:.|:.:.||::......::.:.|||:|..:.: .||..|| ..:.|::|...|.|
Human   125 IKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGA-DYPDELQ-CLDAPVLSQAECEA 187

  Fly   190 ALGSKGQDVHTTNL-CTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPSVYVQVS 253
            :...|    .|.|: |.|.|.||...|..|||||:|....|.|||||| ..|.|.|.|.||.:|.
Human   188 SYPGK----ITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVY 247

  Fly   254 SFITW----IAAN 262
            :::.|    ||||
Human   248 NYVDWIKDTIAAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	78/249 (31%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	76/245 (31%)