Protein Alignment Phae2 and PRSS1

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 86/261 - (32%)
• Similarity: 126/261 - (48%)
• Gaps: 27/261 - (10%)

  Fly    11 LLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLA 75
            ||:...|:.......|. :.::|||.....||.||.||:. .|.|:|..::||..|:|:|.||..
Human     4 LLILTFVAAALAAPFDD-DDKIVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYK 66

  Fly    76 NRNQV-LGS---TLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAA 136
            :|.|| ||.   .::.|:......|...:..|.....:|:         ||.||...:.....|.
Human    67 SRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNN---------DIMLIKLSSRAVINAR 122

  Fly   137 VAPVKLPSSGVRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTT 201
            |:.:.||::......|..:.|||:|:.:.: .||..|| ..:.|::|...|.|:...|    .|:
Human   123 VSTISLPTAPPATGTKCLISGWGNTASSGA-DYPDELQ-CLDAPVLSQAKCEASYPGK----ITS 181

  Fly   202 NL-CTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPSVYVQVSSFITW----IAA 261
            |: |.|.|.||...|..|||||:|....|.|:||||. .|.|.|.|.||.:|.:::.|    |||
Human   182 NMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTIAA 245

  Fly   262 N 262
            |
Human   246 N 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	80/238 (34%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	77/232 (33%)