Protein Alignment Phae2 and KLK15

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 82/275 - (29%)
• Similarity: 117/275 - (42%)
• Gaps: 30/275 - (10%)

  Fly     1 MWRHRHLATILLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSN 65
            ||        |||.:.....|..|  |...:::.|...|.:|.|:.|::...|...|.|::|:.:
Human     1 MW--------LLLTLSFLLASTAA--QDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPH 55

  Fly    66 WLVTAAHCLANRNQVLGSTLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTA 130
            |:::||||.:...:|.     .|...:.......|.|..:..:.:..|...:...||.|:.....
Human    56 WVLSAAHCQSRFMRVR-----LGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQP 115

  Fly   131 FTWTAAVAPVKLPSSGVRPTGKADLFGWGSTSKTNSP----------SYPKTLQEAKNIPIISLD 185
            ......|.|..||:....|.....:.|||..|. |.|          |.|.||..| ||.|||..
Human   116 ARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSH-NEPGTAGSPRSQVSLPDTLHCA-NISIISDT 178

  Fly   186 SCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPSVYV 250
            ||..:...:   :..|.:|.|....|...|..|||||||.|.:|.||||||.:||.....|.||.
Human   179 SCDKSYPGR---LTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYT 240

  Fly   251 QVSSFITWIAANQKK 265
            :|..::.||....|:
Human   241 KVCHYLEWIRETMKR 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	73/239 (31%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	71/233 (30%)