Protein Alignment Phae2 and KLK2

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 89/284 - (31%)
• Similarity: 127/284 - (44%)
• Gaps: 46/284 - (16%)

  Fly     1 MWRHRHLATILLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSN 65
            ||.       |:|::.:|.|...|:...:.|:|||.....:|.|:.|::...|..:|...:::..
Human     1 MWD-------LVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQ 58

  Fly    66 WLVTAAHCLANRNQVLGSTLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTV-----------P 119
            |::||||||...:||.     .|...:.....|.|:..::|...:.||....:           .
Human    59 WVLTAAHCLKKNSQVW-----LGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSS 118

  Fly   120 YDIGL--IYTPTAFTWTAAV--APVKLPSSGVRPTGKADLFGWGSTSKTNSPS---YPKTLQEAK 177
            :|:.|  :..|...|....|  .|.:.|:.|.  |..|.  ||||.    .|.   .|::|| ..
Human   119 HDLMLLRLSEPAKITDVVKVLGLPTQEPALGT--TCYAS--GWGSI----EPEEFLRPRSLQ-CV 174

  Fly   178 NIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQ 242
            ::.::|.|.||.|...|   |....||.|..|||...|..|||||||...||.||.|||..||..
Human   175 SLHLLSNDMCARAYSEK---VTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCAL 236

  Fly   243 PNSPSVYVQVSSFITW----IAAN 262
            |..|:||.:|..:..|    ||||
Human   237 PEKPAVYTKVVHYRKWIKDTIAAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	79/251 (31%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	77/247 (31%)