Protein Alignment Phae2 and KLK1

DIOPT Version :9

• Sequence 1: NP_001285871.1
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 88/271 - (32%)
• Similarity: 123/271 - (45%)
• Gaps: 29/271 - (10%)

  Fly     1 MWRHRHLATILLLAVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSN 65
            ||       .|:|.:.:|.|...|....:.|:|||.....:|.|:..::.:..|..|...:::..
Human     1 MW-------FLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQ 58

  Fly    66 WLVTAAHCLANRNQVLGSTLVAGSIAVAGTASTTQ----KRQITHYVIN-DLYTGGT------VP 119
            |::|||||:::..|     |..|...:....:|.|    .....|...| .|....|      ..
Human    59 WVLTAAHCISDNYQ-----LWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYS 118

  Fly   120 YDIGLI-YTPTAFTWTAAVAPVKLPSSGVRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIIS 183
            :|:.|: .|..|.|.|.||..|:||:............||||....|. |:|..|| ..::.|:.
Human   119 HDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENF-SFPDDLQ-CVDLKILP 181

  Fly   184 LDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPSV 248
            .|.|..|...|..|.   .||.|.|.||...|..||||||:...||.|:.|||.:|||.||.|||
Human   182 NDECKKAHVQKVTDF---MLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSV 243

  Fly   249 YVQVSSFITWI 259
            .|:|.|::.||
Human   244 AVRVLSYVKWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	79/239 (33%)
		Tryp_SPc	32..262	CDD:238113	80/240 (33%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	80/240 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850