DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae2 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001285871.1	Gene:	Phae2 / 34638	FlyBaseID:	FBgn0263235	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	82/254 - (32%)
Similarity:	123/254 - (48%)	Gaps:	27/254 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 CVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLANRNQV 80
            |:..|..|...    |||||..|:|:|.|:.||:||...|.|..:|::.:|::|||||......|
  Rat   234 CLDCGKSLKTT----RVVGGVEASADSWPWQVSIQYNKQHVCGGSILDHHWILTAAHCFRKYLDV 294

  Fly    81 LGSTLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVPY-----DIGLIYTPTAFTWTAAVAPV 140
            ....:.|||..:..:.|..         :..::.....|.     ||.|:......|::.:|.|:
  Rat   295 SSWKVRAGSNKLGNSPSLP---------VAKIFIAEPNPLQPKEKDIALVKLKMPLTFSGSVRPI 350

  Fly   141 KLPSSG--VRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNL 203
            .||.|.  :.||....:.|||.|.: |......||.:| ::.:|....|.|....:| :|....|
  Rat   351 CLPFSDEELIPTMPVWVIGWGFTEE-NGGKMSDTLLQA-SVQVIDSARCNAEDAYQG-EVTAGML 412

  Fly   204 CTGPLTGGTSFCTSDSGGPLVQGN---VLIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            |.|...||...|..||||||:...   .::|||||| ..||.|::|.||.:|::::.||
  Rat   413 CAGTPQGGKDTCQGDSGGPLMYHYDKWQVVGIVSWG-YGCGSPSTPGVYTKVTAYLDWI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	77/237 (32%)
Phae2	NP_001285871.1	Tryp_SPc	32..262	CDD:238113	78/238 (33%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	1/3 (33%)
		Tryp_SPc	245..470	CDD:214473	77/237 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341154
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840