Protein Alignment Phae2 and PRSS53

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 82/330 - (24%)
• Similarity: 126/330 - (38%)
• Gaps: 102/330 - (30%)

  Fly     8 ATILLLAV------CVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNW 66
            ||:|:..:      |..:|.|....| ||..|.|:      .|:..|::..|.|.|:.:::...|
Human    14 ATVLMEGLQAAQRACGQRGPGPPKPQ-EGNTVPGE------WPWQASVRRQGAHICSGSLVADTW 71

  Fly    67 LVTAAHC--------LANRNQVLGST----LVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVP 119
            ::|||||        |.:.:.||||.    |..|:..| |.|:....|...|      |:.|:
Human    72 VLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEV-GVAALQLPRAYNH------YSQGS-- 127

  Fly   120 YDIGLIYT--PTAFTWTAAVAPVKLPSSGVR-PTGKAD-LFGWG--------------------- 159
             |:.|:..  ||..|      |:.||....| |.|.:. ..||.
Human   128 -DLALLQLAHPTTHT------PLCLPQPAHRFPFGASCWATGWDQDTSDGKCWPRLKLGEALCLP 185

  Fly   160 --STSKTNSPSY--------------------PKTLQEAKNIPIISLDSCAAALGSKGQDVHTTN 202
              :.|..|.|.:                    |.||:..: :.:||..:|........|. |.:|
Human   186 SVTVSAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLR-LRLISRPTCNCIYNQLHQR-HLSN 248

  Fly   203 ------LCTGPLTGGTSFCTSDSGGPLV----QGN-VLIGIVSWGKLPCGQPNSPSVYVQVSSFI 256
                  ||.||..|....|..|||||::    .|: |..||:|:.. .|.|.::|.:....::..
Human   249 PARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFAS-SCAQEDAPVLLTNTAAHS 312

  Fly   257 TWIAA 261
            :|:.|
Human   313 SWLQA 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	73/300 (24%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	72/298 (24%)
		Tryp_SPc	359..>512	CDD:473915