DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae2 and Prss53

DIOPT Version :9

Sequence 1:	NP_001285871.1	Gene:	Phae2 / 34638	FlyBaseID:	FBgn0263235	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	280	Identity:	75/280 - (26%)
Similarity:	114/280 - (40%)	Gaps:	52/280 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 HRHLATILLLA----------VCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCA 58
            |.|.|..|:.|          .||:.||        .|..|.:|.|.:..|:...:::.|...|.
Mouse   271 HVHEAAFLVQAPGVVKMSDENSCVACGS--------LRSAGPQAGALSQWPWDARLKHHGKLACG 327

  Fly    59 ANIINSNWLVTAAHCLANRNQVLGSTLVAGSIAV-AGTASTTQKRQITHYVINDLYTGGTVPYDI 122
            ..:::...::|||||...|     .||...|:.: ||......|:.|.|    ..||.....||:
Mouse   328 GALVSEVVVLTAAHCFIGR-----QTLEEWSVGLGAGPEEWGLKQLILH----GAYTHPEGGYDV 383

  Fly   123 GLIYTPTAFTWTAAVAPVKLPSSGVR-PTGKADLFGW--GSTSKTNSPSYPKTLQEAKNIPIISL 184
            ..:......|....:.|:.||.:... |.|:   .||  |.|.|... :||:|      :|:..|
Mouse   384 AFLLLAQPVTLGPGLRPLCLPYADHHLPDGE---HGWVLGLTQKAGI-NYPQT------VPVTVL 438

  Fly   185 DSCA-----AALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGPLV---QGN-VLIGIVSWGKLPC 240
            ...|     ||.|..|..:....:|| .:.|....|...||.|||   :|. .|:|:.|:|. .|
Mouse   439 GPMACSRQHAAPGGTGIPILPGMVCT-TVVGEPPHCEGLSGAPLVHEIRGTWFLVGLHSFGD-TC 501

  Fly   241 GQPNSPSVYVQVSSFITWIA 260
            .....|:|:..:|::..||:
Mouse   502 QSSAKPAVFAALSAYEDWIS 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	64/240 (27%)
Phae2	NP_001285871.1	Tryp_SPc	32..262	CDD:238113	65/242 (27%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113	75/280 (27%)
		Tryp_SPc	311..522	CDD:238113	62/232 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010