DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae2 and Tmprss6

DIOPT Version :9

Sequence 1:	NP_001285871.1	Gene:	Phae2 / 34638	FlyBaseID:	FBgn0263235	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_006242057.1	Gene:	Tmprss6 / 315388	RGDID:	1307138	Length:	811	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	80/251 - (31%)
Similarity:	109/251 - (43%)	Gaps:	30/251 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLANRNQVLGS----TL 85
            |..|..|:|||..::....|:..|:|..|.|.|...:|...|::|||||.  :...:.|    |:
  Rat   570 LQGPSSRIVGGAMSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCF--QEDSMASPRLWTV 632

  Fly    86 VAGSIAV----AGTASTTQKRQITH-YVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLP-- 143
            ..|.:..    .|..|....|...| |...|.:     .||:.|:.......::|.|.||.||
  Rat   633 FLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSH-----DYDVALLQLDHPVVYSATVRPVCLPAR 692

  Fly   144 SSGVRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNLCTGPL 208
            |....|.....:.|||:..:....|  .|||:. ::.:|..|.|..|.   ...|....||.|..
  Rat   693 SHFFEPGQHCWITGWGAQREGGPGS--STLQKV-DVQLIPQDLCNEAY---RYQVTPRMLCAGYR 751

  Fly   209 TGGTSFCTSDSGGPLV----QGN-VLIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            .|....|..|||||||    .|. .|.|:|||| |.||:||...||.:|:..:.||
  Rat   752 KGKKDACQGDSGGPLVCKEPSGRWFLAGLVSWG-LGCGRPNFFGVYTRVTRVVNWI 806

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	76/243 (31%)
Phae2	NP_001285871.1	Tryp_SPc	32..262	CDD:238113	77/244 (32%)
Tmprss6	XP_006242057.1	SEA	88..185	CDD:279699
		LDLa	459..489	CDD:238060
		LDLa	495..525	CDD:238060
		Ldl_recept_a	529..566	CDD:278486
		Tryp_SPc	576..806	CDD:214473	76/243 (31%)
		Tryp_SPc	577..809	CDD:238113	77/244 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010