Protein Alignment Phae2 and GZMK

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 70/235 - (29%)
• Similarity: 113/235 - (48%)
• Gaps: 8/235 - (3%)

  Fly    32 VVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLANRNQVLGSTLVAGSIAVAGTA 96
            ::|||..:.:|.|::.|:||||.|.|...:|:..|::|||||.....:....|:|.|:.:::...
Human    27 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHSLSKNE 91

  Fly    97 STTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLPS-SGVRPTGKADLFGWGS 160
            ::.|..:|..::.....|......||.|:...||......|..:.:.| :.:|...|..:.|||:
Human    92 ASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGA 156

  Fly   161 TSKTN-SPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNL-CTGPLTGGTSFCTSDSGGPL 223
            |...: .||  .||:|. .:.::|...|.:.....|....|.:: |.|...|....|..||||||
Human   157 TDPDSLRPS--DTLREV-TVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPL 218

  Fly   224 VQGNVLIGIVSWGKLPCGQPNSPSVYVQVS-SFITWIAAN 262
            :...|...|||.|. .||....|.:|..:: .:.|||.:|
Human   219 ICKGVFHAIVSGGH-ECGVATKPGIYTLLTKKYQTWIKSN 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	69/233 (30%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	69/233 (30%)