Protein Alignment Phae2 and KLK13

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 91/277 - (32%)
• Similarity: 129/277 - (46%)
• Gaps: 25/277 - (9%)

  Fly     1 MWRHRHLATILLLAVC--VSQGSGLALDQ--PEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANI 61
            ||....:...|.||:.  |||.|...|:.  ..|.:.||.....:|.|:..::...|...|...:
Human     1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVL 65

  Fly    62 INSNWLVTAAHCLANRNQVLGSTLVAGSIAVAGTASTTQKRQITHYVINDLY----TGGTVPYDI 122
            ::..|::||||||..     |..:..|..|:....:..|.|::.|.:.:..|    |.....:||
Human    66 VHPKWVLTAAHCLKE-----GLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDI 125

  Fly   123 GL--IYTPTAFTWTAAVAPVKLPSSGVRPTGKADLFGWGSTSKTNSP--SYPKTLQEAKNIPIIS 183
            .|  :.:|...|......|:. .::.:.|.....:.|||:|:   ||  :||||||.| ||.:.|
Human   126 MLLELQSPVQLTGYIQTLPLS-HNNRLTPGTTCRVSGWGTTT---SPQVNYPKTLQCA-NIQLRS 185

  Fly   184 LDSCAAALGSKGQDVHTTNLCTGPLTGGTSFCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPSV 248
            .:.|......|..|   ..||.|...||...|..|||||||....|.||||||..|||||:.|.|
Human   186 DEECRQVYPGKITD---NMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGV 247

  Fly   249 YVQVSSFITWIAANQKK 265
            |.:||.::.||....:|
Human   248 YTRVSRYVLWIRETIRK 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	79/237 (33%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	79/235 (34%)