DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phae2 and PRSS54

DIOPT Version :9

Sequence 1:	NP_001285871.1	Gene:	Phae2 / 34638	FlyBaseID:	FBgn0263235	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001073961.1	Gene:	PRSS54 / 221191	HGNCID:	26336	Length:	395	Species:	Homo sapiens

Alignment Length:	275	Identity:	60/275 - (21%)
Similarity:	103/275 - (37%)	Gaps:	81/275 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 DQPEGRVVGGKAAAANSAPYIVSM---QYGGTHYCAANIINSNWLVTAAHCLANRNQVLGSTLVA 87
            |..||.|      ::...|::||:   ||  ||.....|::..|:::.|..:.||..:
Human    42 DPKEGLV------SSMEFPWVVSLQDSQY--THLAFGCILSEFWVLSIASAIQNRKDI------- 91

  Fly    88 GSIAVAGTASTTQKRQITH--YVINDL-----YTGGTVPYDIGLIYTPTAFTWTAAV-------- 137
              :.:.| .|.....:|.|  |.:|.:     :...::..:|.|:.|.||..:...|
Human    92 --VVIVG-ISNMDPSKIAHTEYPVNTIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGR 153

  Fly   138 ---APVKLPSSGVRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSC------AAALGS 193
               .|..|.:..|.        ||..||.|.:   ..|:...:.|.:..||.|      ....||
Human   154 MLHTPPVLQNCWVS--------GWNPTSATGN---HMTMSVLRKIFVKDLDMCPLYKLQKTECGS 207

  Fly   194 KGQDVHTTNLCTGPLTGGTSFCTSDSGGPLV----QGN--VLIGIVSWGKLPCGQPNSPS--VYV 250
            ..:: .|...|.|           |.|.|::    |.:  ||.|::::|...|     |.  :|.
Human   208 HTKE-ETKTACLG-----------DPGSPMMCQLQQFDLWVLRGVLNFGGETC-----PGLFLYT 255

  Fly   251 QVSSFITWIAANQKK 265
            :|..:..||.:..::
Human   256 KVEDYSKWITSKAER 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	55/262 (21%)
Phae2	NP_001285871.1	Tryp_SPc	32..262	CDD:238113	57/264 (22%)
PRSS54	NP_001073961.1	Tryp_SPc	52..264	CDD:214473	54/251 (22%)
		Tryp_SPc	52..264	CDD:238113	54/251 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147448
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930