DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phae2 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_001285871.1	Gene:	Phae2 / 34638	FlyBaseID:	FBgn0263235	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_663378.1	Gene:	Tmprss4 / 214523	MGIID:	2384877	Length:	435	Species:	Mus musculus

Alignment Length:	243	Identity:	81/243 - (33%)
Similarity:	120/243 - (49%)	Gaps:	15/243 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINSNWLVTAAHCLANRNQVLGSTLV 86
            |.:|..|  |||||..|..:|.|:.||:||...|.|..:|::.:|::|||||......|....:.
Mouse   195 GKSLKTP--RVVGGVEAPVDSWPWQVSIQYNKQHVCGGSILDPHWILTAAHCFRKYLDVSSWKVR 257

  Fly    87 AGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDIGLIYTPTAFTWTAAVAPVKLPSSG--VRP 149
            ||| .:.|.:.:....:|.....|.||   ....||.|:......|::.:|.|:.||.|.  :.|
Mouse   258 AGS-NILGNSPSLPVAKIFIAEPNPLY---PKEKDIALVKLQMPLTFSGSVRPICLPFSDEVLVP 318

  Fly   150 TGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDSCAAALGSKGQDVHTTNLCTGPLTGGTSF 214
            .....:.|||.|.:.........||  .::.:|....|.|....:| :|....||.|...||...
Mouse   319 ATPVWVIGWGFTEENGGKMSDMLLQ--ASVQVIDSTRCNAEDAYEG-EVTAEMLCAGTPQGGKDT 380

  Fly   215 CTSDSGGPLVQGN---VLIGIVSWGKLPCGQPNSPSVYVQVSSFITWI 259
            |..||||||:..:   .::||||||. .||.|::|.||.:|::::.||
Mouse   381 CQGDSGGPLMYHSDKWQVVGIVSWGH-GCGGPSTPGVYTKVTAYLNWI 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_001285871.1	Tryp_SPc	31..259	CDD:214473	76/232 (33%)
Phae2	NP_001285871.1	Tryp_SPc	32..262	CDD:238113	77/233 (33%)
Tmprss4	NP_663378.1	LDLa	56..90	CDD:238060
		SRCR_2	106..195	CDD:295335	81/243 (33%)
		Tryp_SPc	202..427	CDD:214473	76/232 (33%)
		Tryp_SPc	203..430	CDD:238113	77/233 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840