Protein Alignment Phae2 and CFD

DIOPT Version :10

• Sequence 1: NP_609551.2
• Gene: Phae2 / 34638
• FlyBaseID: FBgn0263235
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 79/272 - (29%)
• Similarity: 124/272 - (45%)
• Gaps: 34/272 - (12%)

  Fly     2 WRHRHLATILLL--AVCVSQGSGLALDQPEGRVVGGKAAAANSAPYIVSMQYGGTHYCAANIINS 64
            |  ..||.::||  |.|..:....|. .|.||::||:.|.|::.||:.|:|..|.|.|...::..
Human     4 W--ERLAVLVLLGAAACGEEAWAWAA-PPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAE 65

  Fly    65 NWLVTAAHCLAN----RNQVLGSTLVAGSIAVAGTASTTQKRQITHYVINDLYTGGTVPYDIGLI 125
            .|:::|||||.:    :.|||     .|:.:::....:.:...:...|.:......|:.:|:.|:
Human    66 QWVLSAAHCLEDAADGKVQVL-----LGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLL 125

  Fly   126 YTPTAFTWTAAVAPVKLP----SSGVRPTGKADLFGWGSTSKTNSPSYPKTLQEAKNIPIISLDS 186
            ......|...||.|  ||    ...|.|....|:.|||..:  ::...|.:||... :|::...:
Human   126 QLSEKATLGPAVRP--LPWQRVDRDVAPGTLCDVAGWGIVN--HAGRRPDSLQHVL-LPVLDRAT 185

  Fly   187 CAAALGSKGQDVHTTNLCTGPLTGGTS----FCTSDSGGPLVQGNVLIGIVSWGKLPCGQPNSPS 247
            |       .:..|.....|..|....|    .|..|||||||.|.||.|:|:.|...||....|.
Human   186 C-------NRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPG 243

  Fly   248 VYVQVSSFITWI 259
            :|.:|:|:..||
Human   244 IYTRVASYAAWI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phae2	NP_609551.2	Tryp_SPc	32..262	CDD:238113	68/240 (28%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	68/240 (28%)